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COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence – “viral load was tenfold higher in P.1 infections than in non-P.1”.

COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence – Nature Medicine  

The post COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence – “viral load was tenfold higher in P.1 infections than in non-P.1”. appeared first on Links Medicus.

Estimating infectiousness throughout SARS-CoV-2 infection course – 8% of subjects had very high viral loads, one-third of whom had little to no symptoms; in individuals infected with the B.1.1.7 variant, average viral loads were 10 times higher.

Estimating infectiousness throughout SARS-CoV-2 infection course – Science Commentary: Estimating infectiousness of SARS-CoV-2: New study on viral load – Universitätsmedizin Berlin   Commentary on Twitter Of 25,000+ people who tested positive for #COVID19 in Germany, 8% had very high viral loads; about a third of these had little to no symptoms. The results suggest asymptomatic […]

The post Estimating infectiousness throughout SARS-CoV-2 infection course – 8% of subjects had very high viral loads, one-third of whom had little to no symptoms; in individuals infected with the B.1.1.7 variant, average viral loads were 10 times higher. appeared first on Links Medicus.

What scientists know about new, fast-spreading coronavirus variants.

What scientists know about new, fast-spreading coronavirus variants – Nature  

The post What scientists know about new, fast-spreading coronavirus variants. appeared first on Links Medicus.

Short review: Diagnosis and management of acute respiratory distress syndrome

Diagnosis and management of acute respiratory distress syndrome – Canadian Medical Association Journal   Commentary on Twitter #ARDS is an important priority in our ICUs at the moment. Our @CMAJ review looks at diagnosis, and provides a guideline-based approach to management, along with a discussion on #COVID19 ARDS. A great primer for those new to […]

The post Short review: Diagnosis and management of acute respiratory distress syndrome appeared first on Links Medicus.

Perspective | Coronavirus: so many variants, but vaccines are still effective.

Coronavirus: so many variants, but vaccines are still effective – The Conversation  

The post Perspective | Coronavirus: so many variants, but vaccines are still effective. appeared first on Links Medicus.

Mild COVID-19 induces lasting antibody protection, study finds.

Mild COVID-19 induces lasting antibody protection, study finds – Washington University School of Medicine Original study: SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans – Nature   Commentary on Twitter (thread – click for more) Just published @nature After even mild covid infections there are, in addition to memory B cells, bone marrow […]

The post Mild COVID-19 induces lasting antibody protection, study finds. appeared first on Links Medicus.

Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.

Effectiveness of Tocilizumab in Patients Hospitalized With COVID-19: A Follow-up of the CORIMUNO-TOCI-1 Randomized Clinical Trial – JAMA Internal Medicine  

The post Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less. appeared first on Links Medicus.

Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19.

Vitamin D supplementation for the treatment of COVID‐19: a living systematic review – Cochrane Library Summary: Is vitamin D an effective and safe treatment for COVID-19? – Cochrane Library  

The post Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19. appeared first on Links Medicus.

Admission respiratory status predicts mortality in COVID-19 – hypoxemic patients (oxygen saturation less than 92%) had a 1.8- to 4.0-fold increased mortality risk; those with respiratory rates over 22 breaths per minute were at 1.9- to 3.2-fold elevated m

Admission respiratory status predicts mortality in COVID-19 – Influenza and Other Respiratory Virus Commentaries: COVID-19 mortality associated with 2 signs easily measured at home – University of Washington School of Medicine AND Low oxygen levels, shallow breathing tied to COVID death – CIDRAP   2 signs easily measured at home can indicate increased Covid mortality […]

The post Admission respiratory status predicts mortality in COVID-19 – hypoxemic patients (oxygen saturation less than 92%) had a 1.8- to 4.0-fold increased mortality risk; those with respiratory rates over 22 breaths per minute were at 1.9- to 3.2-fold elevated mortality risk. appeared first on Links Medicus.

A deep learning algorithm can estimate malignancy risk of pulmonary nodules detected at low-dose screening CT.

Deep Learning for Malignancy Risk Estimation of Pulmonary Nodules Detected at Low-Dose Screening CT – Radiology Commentaries: AI predicts lung cancer risk – Radiological Society of North America AND AI Takes LDCT Further for Lung Cancer Prediction – Diagnostic Imaging   Commentary on Twitter A deep learning algorithm can have a discriminative performance comparable to […]

The post A deep learning algorithm can estimate malignancy risk of pulmonary nodules detected at low-dose screening CT. appeared first on Links Medicus.

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