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Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19.

Vitamin D supplementation for the treatment of COVID‐19: a living systematic review – Cochrane Library Summary: Is vitamin D an effective and safe treatment for COVID-19? – Cochrane Library  

The post Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation as a treatment of COVID‐19. appeared first on Links Medicus.

Admission respiratory status predicts mortality in COVID-19 – hypoxemic patients (oxygen saturation less than 92%) had a 1.8- to 4.0-fold increased mortality risk; those with respiratory rates over 22 breaths per minute were at 1.9- to 3.2-fold elevated m

Admission respiratory status predicts mortality in COVID-19 – Influenza and Other Respiratory Virus Commentaries: COVID-19 mortality associated with 2 signs easily measured at home – University of Washington School of Medicine AND Low oxygen levels, shallow breathing tied to COVID death – CIDRAP   2 signs easily measured at home can indicate increased Covid mortality […]

The post Admission respiratory status predicts mortality in COVID-19 – hypoxemic patients (oxygen saturation less than 92%) had a 1.8- to 4.0-fold increased mortality risk; those with respiratory rates over 22 breaths per minute were at 1.9- to 3.2-fold elevated mortality risk. appeared first on Links Medicus.

A deep learning algorithm can estimate malignancy risk of pulmonary nodules detected at low-dose screening CT.

Deep Learning for Malignancy Risk Estimation of Pulmonary Nodules Detected at Low-Dose Screening CT – Radiology Commentaries: AI predicts lung cancer risk – Radiological Society of North America AND AI Takes LDCT Further for Lung Cancer Prediction – Diagnostic Imaging   Commentary on Twitter A deep learning algorithm can have a discriminative performance comparable to […]

The post A deep learning algorithm can estimate malignancy risk of pulmonary nodules detected at low-dose screening CT. appeared first on Links Medicus.

Indirect Protection by Reducing Transmission: Ending the Pandemic with SARS-CoV-2 Vaccination – “Tell the hesitant: the vaccines protect both you and protect others — a lot!”

Indirect Protection by Reducing Transmission: Ending the Pandemic with SARS-CoV-2 Vaccination – Open Forum Infectious Diseases   Commentary on Twitter *Strongly* recommend this comprehensive review of just how much COVID19 vaccines reduce the risk of transmitting the virus to others. Tell the hesitant: the vaccines protect both you and protect others — a lot! @mugecevik […]

The post Indirect Protection by Reducing Transmission: Ending the Pandemic with SARS-CoV-2 Vaccination – “Tell the hesitant: the vaccines protect both you and protect others — a lot!” appeared first on Links Medicus.

Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – moderate-to-severe COVID-19 was associated with age 25 years and older, healthcare occupation, pre-pregnancy obesity, chronic lung disease, chronic hypertension,

Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – Surveillance for Emerging Threats to Mothers and Babies Network, 22 state, local, and territorial health departments, March 29, 2020 -March 5, 2021 – Clinical Infectious Diseases  

The post Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – moderate-to-severe COVID-19 was associated with age 25 years and older, healthcare occupation, pre-pregnancy obesity, chronic lung disease, chronic hypertension, and pregestational diabetes mellitus. appeared first on Links Medicus.

Using resources wisely in the COVID-19 pandemic: an international list of Choosing Wisely recommendations.

Using resources wisely in the COVID-19 pandemic: an international list of Choosing Wisely recommendations – Journal of Evidence-Based Healthcare  

The post Using resources wisely in the COVID-19 pandemic: an international list of Choosing Wisely recommendations. appeared first on Links Medicus.

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection.

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection – Nature Medicine Commentary: Scientists find new way of predicting COVID-19 vaccine efficacy – University of New South Wales   Commentary on Twitter (thread – click for more) Just published @NatureMedicine: For 7 vaccines, the neutralizing antibody levels are highly predictive of […]

The post Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection. appeared first on Links Medicus.

M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”.

Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials – Intensive Care Medicine   Commentary on Twitter Tocilizumab as IL-6 antagonist in hospitalized #COVID19 pts, SR/MA/TSA:➡️10 RCTs/6493 pts (52.2% ➡️ tocilizumab)➡️some evidence suggests tocilizumab may be associated with short-term mortality benefit➡️tocilizumab may prevent disease progression to MVhttps://t.co/sWR4Y351sl pic.twitter.com/JPD31Nb5rn — Intens Care […]

The post M-A: Tocilizumab in COVID-19 – “For hospitalized COVID-19 patients, there is some evidence that tocilizumab use may be associated with a short-term mortality benefit, but further high-quality data are required”. appeared first on Links Medicus.

[Preprint] Pfizer and AstraZeneca Vaccines effective against B.1.617.2 variant after 2 doses.

News release: Vaccines highly effective against B.1.617.2 variant after 2 doses – Public Health England Original study: Effectiveness of COVID-19 vaccines against the B.1.617.2 variant – Public Health England Commentary: Covid: Pfizer and AstraZeneca jabs effective against Indian variant – study – BBC  

The post [Preprint] Pfizer and AstraZeneca Vaccines effective against B.1.617.2 variant after 2 doses. appeared first on Links Medicus.

[Preprint] Effectiveness of the CoronaVac vaccine in the elderly population during a P.1 variant-associated epidemic of COVID-19 in Brazil – “CoronaVac was 42% effective in the real-world setting of extensive P.1 transmission, but significant protection w