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Covid-19: Pfizer-BioNTech vaccine is “likely” responsible for deaths of some elderly patients, Norwegian review finds.

Covid-19: Pfizer-BioNTech vaccine is “likely” responsible for deaths of some elderly patients, Norwegian review finds – The BMJ   Commentary on Twitter The Pfizer-BioNTech covid-19 vaccine is “likely” to have been responsible for at least 10 deaths of frail elderly people in nursing homes in Norway, an expert review concluded, although it emphasised considerable uncertainty […]

The post Covid-19: Pfizer-BioNTech vaccine is “likely” responsible for deaths of some elderly patients, Norwegian review finds. appeared first on Links Medicus.

RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to

Safety, Immunogenicity, and Efficacy of the BNT162b2 Covid-19 Vaccine in Adolescents – New England Journal of Medicine Related: [Press release – not published yet] Pfizer-BioNTech vaccine 100% effective against Covid-19 in adolescents   Commentary on Twitter The 12-15 year-olds mRNA vaccine randomized, placebo-controlled clinical trial is published @NEJM today [@BioNTech_Group/@Pfizer]https://t.co/7GlgC9xdd0—100% efficacy (95% CI 75,100)—1.8 X […]

The post RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site pain (in 79 to 86% of participants), fatigue (in 60 to 66%), and headache (in 55 to 65%). appeared first on Links Medicus.

Lab study found CoronaVac serum neutralization efficiency was significantly decreased against B.1.526, P.1, and B1.351 SARS-CoV-2 variants.

Serum neutralising activity against SARS-CoV-2 variants elicited by CoronaVac – The Lancet Infectious Diseases  

The post Lab study found CoronaVac serum neutralization efficiency was significantly decreased against B.1.526, P.1, and B1.351 SARS-CoV-2 variants. appeared first on Links Medicus.

COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.

Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial – The Lancet Respiratory Medicine Invited Commentary: Exploiting an early immunological window of opportunity in COVID-19 – The Lancet Respiratory Medicine  

The post COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required. appeared first on Links Medicus.

Global cardiovascular organizations release joint opinion on achieving the ‘tobacco endgame’.

Statement: The tobacco endgame—eradicating a worsening epidemic: a joint opinion from the American Heart Association, World Heart Federation, American College of Cardiology, and the European Society of Cardiology News release: Global cardiovascular organizations release joint opinion on achieving the ‘tobacco endgame’  – American College of Cardiology Commentary: The Tobacco Endgame—Eradicating a Worsening Epidemic – American […]

The post Global cardiovascular organizations release joint opinion on achieving the ‘tobacco endgame’. appeared first on Links Medicus.

Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June.

Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June – CNBC   Commentary on Twitter BREAKING: Moderna study of more than 3,700 12- to 17-year olds found 100% effficacy in those who received 2-dose #covid19 #vaccine, no significant safety problems. Will apply for FDA authorization.https://t.co/l0MHiLjCcA — […]

The post Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June. appeared first on Links Medicus.

Can people vaccinated against COVID-19 still spread the coronavirus? – “Preliminary evidence seems to suggest the COVID-19 vaccines make it less likely someone who’s vaccinated will transmit the coronavirus”.

Can people vaccinated against COVID-19 still spread the coronavirus? – The Conversation Related: Indirect Protection by Reducing Transmission: Ending the Pandemic with SARS-CoV-2 Vaccination – “Tell the hesitant: the vaccines protect both you and protect others — a lot!”  

The post Can people vaccinated against COVID-19 still spread the coronavirus? – “Preliminary evidence seems to suggest the COVID-19 vaccines make it less likely someone who’s vaccinated will transmit the coronavirus”. appeared first on Links Medicus.

[Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19.

Single-dose SARS-CoV-2 vaccine in a prospective cohort of COVID-19 patients – medRxiv See also: SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors – EClinicalMedicine Related: Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19   Commentaries on Twitter If you had prior covid and […]

The post [Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19. appeared first on Links Medicus.

COVID Morbidity – The emerging burden of long COVID is significant, and needs to be considered when evaluating the risk vs. benefit of pandemic measures.

Count the cost of disability caused by COVID-19 – “Focusing only on cases and deaths hides the pandemic’s lasting health burden on people, societies and economies”.