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Case report: Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT).

Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) – Journal of Thrombosis and Haemostasis Commentary: COVID-19 vaccination: Thrombosis can be prevented by prompt treatment, researchers report – Medical University of Vienna  

The post Case report: Successful treatment of vaccine-induced prothrombotic immune thrombocytopenia (VIPIT). appeared first on Links Medicus.

WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic.

WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic – Nature Related: WHO validates Sinovac-CoronaVac COVID-19 vaccine for emergency use and issues interim policy recommendations. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.  

The post WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. appeared first on Links Medicus.

Six months of COVID vaccines: what 1.7 billion doses have taught scientists.

Six months of COVID vaccines: what 1.7 billion doses have taught scientists – Nature See also: Coronavirus (COVID-19) Vaccinations – Our World in Data   Related commentary on Twitter • To administer the first half a billion vaccines took 113 days• The second half a billion 30 days• The third half a billion 23 days• […]

The post Six months of COVID vaccines: what 1.7 billion doses have taught scientists. appeared first on Links Medicus.

Study shows reduced neutralizing antibody activity induced by Pfizer–BioNTech vaccine against SARS-CoV-2 variants of concern B.1.617.2 (Delta) and B.1.351 (Beta).

Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2  and B.1.351 (Beta) by BNT162b2 vaccination – The Lancet Commentary: Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant – The Francis Crick Institute   Commentary on Twitter (thread – click for more) “Immune escape” in #DeltaVariant. That’s the latest finding – that #B16172 is as […]

The post Study shows reduced neutralizing antibody activity induced by Pfizer–BioNTech vaccine against SARS-CoV-2 variants of concern B.1.617.2 (Delta) and B.1.351 (Beta). appeared first on Links Medicus.

RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased b

Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial – The Lancet Related: #ACC21 – [Not published yet] RCT: Among hospitalized patients with Covid-19 and elevated D-Dimer, therapeutic anticoagulation with Rivaroxaban 20 mg was not associated with improved outcomes and resulted in […]

The post RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk. appeared first on Links Medicus.

ANCA-Associated Vasculitis: An Update.

ANCA-Associated Vasculitis: An Update – Journal of Clinical Medicine  

The post ANCA-Associated Vasculitis: An Update. appeared first on Links Medicus.

RCT: Among patients with ANCA-associated vasculitis without severe glomerulonephritis or alveolar hemorrhage treated with Rituximab, a reduced-dose glucocorticoids regimen (prednisolone 0.5 mg/kg/d) was noninferior to a high-dose glucocorticoid regimen (p

Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients.

Effects of early extubation followed by noninvasive ventilation versus standard extubation on the duration of invasive mechanical ventilation in hypoxemic non-hypercapnic patients: a systematic review and individual patient data meta-analysis of randomized controlled trials – Critical Care  

The post Target arterial PO2 according to the underlying pathology: a mini-review of the available data in mechanically ventilated patients. appeared first on Links Medicus.

M-A: In hypoxemic non-hypercapnic patients, early extubation followed by noninvasive ventilation can reduce the total number of days of invasive mechanical ventilation (mean difference, − 2.04 days), without effects in ICU mortality.

Effects of early extubation followed by noninvasive ventilation versus standard extubation on the duration of invasive mechanical ventilation in hypoxemic non-hypercapnic patients: a systematic review and individual patient data meta-analysis of randomized controlled trials – Critical Care  

The post M-A: In hypoxemic non-hypercapnic patients, early extubation followed by noninvasive ventilation can reduce the total number of days of invasive mechanical ventilation (mean difference, − 2.04 days), without effects in ICU mortality. appeared first on Links Medicus.

In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization.

Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study – PLOS Medicine Commentary: Vitamin D may not provide protection from COVID-19 susceptibility or disease severity, study suggests – PLOS Related: Living systematic review: The evidence is insufficient to determine the benefits and harms of vitamin D supplementation […]

The post In a Mendelian randomization study, researchers found no genetic evidence to support an association between Vitamin D levels and COVID-19 susceptibility, severity, or hospitalization. appeared first on Links Medicus.