COLCORONA RCT: Colchicine for community-treated patients with COVID-19 – findings suggest it may lower death and hospital admission rates, but further studies are required.
Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial – The Lancet Respiratory Medicine Invited Commentary: Exploiting an early immunological window of opportunity in COVID-19 – The Lancet Respiratory Medicine
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Global cardiovascular organizations release joint opinion on achieving the ‘tobacco endgame’.
Statement: The tobacco endgame—eradicating a worsening epidemic: a joint opinion from the American Heart Association, World Heart Federation, American College of Cardiology, and the European Society of Cardiology News release: Global cardiovascular organizations release joint opinion on achieving the ‘tobacco endgame’ – American College of Cardiology Commentary: The Tobacco Endgame—Eradicating a Worsening Epidemic – American […]
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Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June.
Moderna says its Covid vaccine is 100% effective in teens, plans to seek FDA OK in early June – CNBC Commentary on Twitter BREAKING: Moderna study of more than 3,700 12- to 17-year olds found 100% effficacy in those who received 2-dose #covid19 #vaccine, no significant safety problems. Will apply for FDA authorization.https://t.co/l0MHiLjCcA — […]
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Can people vaccinated against COVID-19 still spread the coronavirus? – “Preliminary evidence seems to suggest the COVID-19 vaccines make it less likely someone who’s vaccinated will transmit the coronavirus”.
Can people vaccinated against COVID-19 still spread the coronavirus? – The Conversation Related: Indirect Protection by Reducing Transmission: Ending the Pandemic with SARS-CoV-2 Vaccination – “Tell the hesitant: the vaccines protect both you and protect others — a lot!”
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[Preprint] More data showing a single-dose SARS-CoV-2 mRNA vaccine may be enough in individuals with previous COVID-19.
Single-dose SARS-CoV-2 vaccine in a prospective cohort of COVID-19 patients – medRxiv See also: SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors – EClinicalMedicine Related: Another study shows a single dose of mRNA vaccine may be enough for patients with previous Covid-19 Commentaries on Twitter If you had prior covid and […]
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COVID Morbidity – The emerging burden of long COVID is significant, and needs to be considered when evaluating the risk vs. benefit of pandemic measures.
COVID Morbidity – Science-Based Medicine
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Count the cost of disability caused by COVID-19 – “Focusing only on cases and deaths hides the pandemic’s lasting health burden on people, societies and economies”.
Count the cost of disability caused by COVID-19 – Nature
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Systematic review of 45 studies including 9751 participants, most of which were hospitalized, found 73% had at least 1 persistent symptom for weeks after Covid-19.
Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review – JAMA Network Open Commentary: Seven out of ten hospitalized COVID-19 patients will have long-haul symptoms – MedicalXpress
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RCT: 2 inactivated SARS-CoV-2 vaccines show efficacy of 72.8% and 78.1% on symptomatic COVID-19 infection in adults.
Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial – JAMA Commentary: China’s Sinopharm Publishes Awaited Covid Vaccine Study Details – Bloomberg Commentary on Twitter (thread – click for more) The #4Humanity phase 3 trial of Sinopharm's Beijing & Wuhan vaccines published in JAMA by @NawalAlKaabi &co […]
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[Preprint] Meta-analysis of RCT: Ivermectin for the treatment of COVID-19 – no effect on all-cause mortality, length of stay, or viral clearance
Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – medRxiv Commentary on Twitter ???PreprintIvermectin for the treatment of #COVID19 : A systematic review & meta-analysis of RCTs10 RCTs1173 patients 8 RCTs➡️ Mild1 RCT ➡️ Moderate1 RCT➡️ Mild& modIvermectin did not reduce all-cause mortality,length of stay or viral […]
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