Systematic review of 45 studies including 9751 participants, most of which were hospitalized, found 73% had at least 1 persistent symptom for weeks after Covid-19.
Assessment of the Frequency and Variety of Persistent Symptoms Among Patients With COVID-19: A Systematic Review – JAMA Network Open Commentary: Seven out of ten hospitalized COVID-19 patients will have long-haul symptoms – MedicalXpress
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RCT: 2 inactivated SARS-CoV-2 vaccines show efficacy of 72.8% and 78.1% on symptomatic COVID-19 infection in adults.
Effect of 2 Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: A Randomized Clinical Trial – JAMA Commentary: China’s Sinopharm Publishes Awaited Covid Vaccine Study Details – Bloomberg Commentary on Twitter (thread – click for more) The #4Humanity phase 3 trial of Sinopharm's Beijing & Wuhan vaccines published in JAMA by @NawalAlKaabi &co […]
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[Preprint] Meta-analysis of RCT: Ivermectin for the treatment of COVID-19 – no effect on all-cause mortality, length of stay, or viral clearance
Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – medRxiv Commentary on Twitter ???PreprintIvermectin for the treatment of #COVID19 : A systematic review & meta-analysis of RCTs10 RCTs1173 patients 8 RCTs➡️ Mild1 RCT ➡️ Moderate1 RCT➡️ Mild& modIvermectin did not reduce all-cause mortality,length of stay or viral […]
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COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence – “viral load was tenfold higher in P.1 infections than in non-P.1”.
COVID-19 in Amazonas, Brazil, was driven by the persistence of endemic lineages and P.1 emergence – Nature Medicine
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Estimating infectiousness throughout SARS-CoV-2 infection course – 8% of subjects had very high viral loads, one-third of whom had little to no symptoms; in individuals infected with the B.1.1.7 variant, average viral loads were 10 times higher.
Estimating infectiousness throughout SARS-CoV-2 infection course – Science Commentary: Estimating infectiousness of SARS-CoV-2: New study on viral load – Universitätsmedizin Berlin Commentary on Twitter Of 25,000+ people who tested positive for #COVID19 in Germany, 8% had very high viral loads; about a third of these had little to no symptoms. The results suggest asymptomatic […]
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What scientists know about new, fast-spreading coronavirus variants.
What scientists know about new, fast-spreading coronavirus variants – Nature
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Short review: Diagnosis and management of acute respiratory distress syndrome
Diagnosis and management of acute respiratory distress syndrome – Canadian Medical Association Journal Commentary on Twitter #ARDS is an important priority in our ICUs at the moment. Our @CMAJ review looks at diagnosis, and provides a guideline-based approach to management, along with a discussion on #COVID19 ARDS. A great primer for those new to […]
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Perspective | Coronavirus: so many variants, but vaccines are still effective.
Coronavirus: so many variants, but vaccines are still effective – The Conversation
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Mild COVID-19 induces lasting antibody protection, study finds.
Mild COVID-19 induces lasting antibody protection, study finds – Washington University School of Medicine Original study: SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans – Nature Commentary on Twitter (thread – click for more) Just published @nature After even mild covid infections there are, in addition to memory B cells, bone marrow […]
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Secondary analysis of RCT finds Tocilizumab was beneficial to patients hospitalized with Covid-19 if CRP levels were greater than 15.0 mg/dL, but not if CRP levels were 15.0 mg/dL or less.
Effectiveness of Tocilizumab in Patients Hospitalized With COVID-19: A Follow-up of the CORIMUNO-TOCI-1 Randomized Clinical Trial – JAMA Internal Medicine
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