[Preprint] Covid-19 B.1.617.2 variant of concern (Delta) is associated with increased transmissibility compared to B.1.1.7 (Alpha) that will rapidly lead to B.1.617.2 becoming the prevailing variant in the UK.
Interim estimates of increased transmissibility, growth rate, and reproduction number of the Covid-19 B.1.617.2 variant of concern in the United Kingdom – medRxiv Related: Covid: Indian variant ‘now dominant’ in the UK – BBC
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RCT: Prophylactic post-exposure prophylaxis with Bamlanivimab reduced the incidence of Covid-19 among residents and staff of skilled nursing and assisted living facilities.
Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial – JAMA Editorial: Bamlanivimab for Prevention of COVID-19
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Another study shows a high frequency of antibiotic use among patients hospitalized with Covid-19 (85.2%), despite low rates of confirmed secondary bacterial infections.
Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, prospective cohort study – The Lancet Microbe Commentaries: Very high use of antibiotics in COVID-19 treatment could be reduced – University of Glasgow AND More evidence of frequent antibiotic use noted […]
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What We Know About the Dangerous COVID B.1.617.2 (Delta) Variant – “the Delta variant may soon become the most dominant COVID strain in the world and lead to rapid outbreaks in countries without high vaccination rates”.
What We Know About the Dangerous COVID B.1.617.2 (Delta) Variant – Intelligencer Commentary on Twitter Good summary of what's presently known about the B.1.617.2 (Delta) variant @NYMag. Important to emphasize 2-dose vaccination effectiveness is high.https://t.co/8cKvR5eBMM w/ @jburnmurdoch @zeynep @macroliter by @chasdanner — Eric Topol (@EricTopol) June 1, 2021
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Countries hit hardest by COVID-19 – estimated mortality countries will have on September 1, 2021.
Countries Hit Hardest by COVID-19 – Think Global Health Commentary on Twitter (thread – click for more) ❓??? Which countries will have the highest mortality from COVID-19 come September 1, 2021? IHME researchers ran the numbers for a new article in @ThinkGlobalHlth ⤵️?https://t.co/d2CFHVzCYX — Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) June 2, […]
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Review: SARS-CoV-2 variants, spike mutations and immune escape.
SARS-CoV-2 variants, spike mutations and immune escape – Nature Reviews Microbiology Commentary on Twitter A new, exceptional review of the #SARSCoV2 major variants, zooming in on the culprit mutations, Δ epitopes/antigens.It concludes there is a "high probability of future mutation-mediated escape from host immunity"https://t.co/D4mFot8Ot5@NatureRevMicro @_wharvey @robertson_lab pic.twitter.com/JgzAhpsviq — Eric Topol (@EricTopol) June 1, 2021 […]
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Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men.
Israel reports link between rare cases of heart inflammation and COVID-19 vaccination in young men – Science (a few articles per month are free) Related: CDC is investigating several reports that teenagers and young adults may have developed myocarditis after receiving mRNA vaccines. Most cases were mild, more often in males than females, more often following […]
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[Press release – not published yet] The city of Serrana in Brazil has seen a 95% drop in Covid-19 deaths after almost all adults were vaccinated with Chinese CoronaVac – The findings suggest the pandemic can be controlled after 75% of people are fully vac
Immunization of Serrana´s population with Butantan´s vaccine has a high decrease of 80% cases and 95% in deaths by COVID – Instituto Butantan Commentaries: Study in Brazilian town shows 95% efficacy of Sinovac’s vaccine in reducing death by COVID-19 – Global Times AND Brazil Covid: Deaths plunge after town’s adults vaccinated – BBC AND Sinovac […]
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WHO validates Sinovac-CoronaVac COVID-19 vaccine for emergency use and issues interim policy recommendations.
WHO validates Sinovac COVID-19 vaccine for emergency use and issues interim policy recommendations – World Health Organization Commentary: WHO grants emergency approval to 2nd Chinese COVID vaccine – MedicalXpress Commentary on Twitter (thread – click for more) WHO today validated the Sinovac-CoronaVac #COVID19 vaccine for emergency use, giving countries, funders, procuring agencies & communities […]
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M-A: Triple vs. dual inhaler therapy in patients with moderate to severe asthma – fewer severe asthma exacerbations, but without significant differences in quality of life or mortality.
Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma: A Systematic Review and Meta-analysis – JAMA (free for a limited period) Commentary on Twitter Among patients with moderate to severe asthma, triple therapy compared with dual therapy was significantly associated with fewer severe asthma exacerbations and modest improvements in asthma […]
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