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The effectiveness of the AstraZeneca vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo was 77.9% against symptomatic Covid-19, 87.6% against hospitalization, and 93.6% against death.

Effectiveness of ChAdOx1 vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo – Nature Medicine   Commentary on Twitter (thread – click for more) Effectiveness of Oxford-AstraZeneca COVID-19 vaccine by dose in over 60s in São Paulo state, published today in @NatureComms with @juliocroda @otavio_ranzani @datcummings as part of the VEBRA COVID-19 […]

The post The effectiveness of the AstraZeneca vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo was 77.9% against symptomatic Covid-19, 87.6% against hospitalization, and 93.6% against death. appeared first on Links Medicus.

Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts.

Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts – The Lancet Respiratory Medicine Commentaries: COVID-19-related ARDS: one disease, two trajectories, and several unanswered questions – The Lancet Respiratory Medicine Respiratory Subphenotypes of COVID-19-Related ARDS – ICU Management & Practice   Commentary on Twitter NEW—At baseline, #COVID19-related #ARDS […]

The post Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts. appeared first on Links Medicus.

RCT: Early treatment of Covid-19 with SARS-CoV-2 neutralizing antibody Sotrovimab is associated with reduced risk of hospitalization.

Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab – New England Journal of Medicine   Commentary on Twitter In this phase 3 trial, sotrovimab or placebo was administered to outpatients within 5 days after the onset of #COVID19 symptoms. Patients receiving sotrovimab had a lower incidence of hospitalization for any reason. #IDTwitter https://t.co/4VcgoK3xac pic.twitter.com/W82v3jNRmB […]

The post RCT: Early treatment of Covid-19 with SARS-CoV-2 neutralizing antibody Sotrovimab is associated with reduced risk of hospitalization. appeared first on Links Medicus.

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial – The Lancet Global Health Commentaries: Expert reaction to study looking at fluvoxamine as a COVID-19 treatment in high-risk outpatients with early-diagnosed COVID-19 – Science Media Centre The TOGETHER Trial: COVID-19 and […]

The post RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19. appeared first on Links Medicus.

COVID super-immunity: one of the pandemic’s great puzzles – “People who have previously recovered from COVID-19 have a stronger immune response after being vaccinated than those who have never been infected. Scientists are trying to find out why”.

Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”.

Mix-and-match COVID vaccines ace the effectiveness test – Nature Related: Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden. Should You Mix and Match Your Booster Shot? Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no […]

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Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination.

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature Related: Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden. Should You Mix and Match Your Booster Shot? Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no […]

The post Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination. appeared first on Links Medicus.

Breakthrough infections occur in those with lower antibody levels.

Breakthrough Infections Occur in Those with Lower Antibody Levels, Israeli Study Shows – NIH Director’s Blog Original study: Covid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine  

The post Breakthrough infections occur in those with lower antibody levels. appeared first on Links Medicus.

Review: Thoracic involvement and imaging patterns in IgG4-related disease.

Thoracic involvement and imaging patterns in IgG4-related disease – European Respiratory Review   Commentary on Twitter Thoracic and lung involvement of IgG4-RD are heterogeneous and underevaluated. Peribronchovascular involvement and lymph node enlargement are most frequent patterns. Interstitial disease pattern seems to be associated with lower rate of treatment response. https://t.co/AMuLjPByut pic.twitter.com/ZmDrz6nK6g — ERS publications (@ERSpublications) October […]

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What It Means To Be Fully Vaccinated.

What It Means To Be Fully Vaccinated – Think Global Health  

The post What It Means To Be Fully Vaccinated. appeared first on Links Medicus.

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