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Complications of critical COVID-19: Diagnostic and therapeutic considerations for the mechanically ventilated patient.

Complications of critical COVID-19: Diagnostic and therapeutic considerations for the mechanically ventilated patient – Chest  

The post Complications of critical COVID-19: Diagnostic and therapeutic considerations for the mechanically ventilated patient. appeared first on Links Medicus.

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern – Science   Commentary from the author on Twitter (thread – click for more) Antibodies come and go, but memory cells are forever (maybe not forever, but at least 6 months). Our latest in @ScienceMagazine: https://t.co/YHHBMrMsTA How long does immune memory last after […]

The post mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern. appeared first on Links Medicus.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’ – Cleveland Clinic Journal of Medicine Related: Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection. WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid). Characterizing long COVID: a living systematic review. Long Covid – The illness narratives. […]

The post Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’. appeared first on Links Medicus.

The effectiveness of the AstraZeneca vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo was 77.9% against symptomatic Covid-19, 87.6% against hospitalization, and 93.6% against death.

Effectiveness of ChAdOx1 vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo – Nature Medicine   Commentary on Twitter (thread – click for more) Effectiveness of Oxford-AstraZeneca COVID-19 vaccine by dose in over 60s in São Paulo state, published today in @NatureComms with @juliocroda @otavio_ranzani @datcummings as part of the VEBRA COVID-19 […]

The post The effectiveness of the AstraZeneca vaccine in older adults during SARS-CoV-2 Gamma variant circulation in São Paulo was 77.9% against symptomatic Covid-19, 87.6% against hospitalization, and 93.6% against death. appeared first on Links Medicus.

Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts.

Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts – The Lancet Respiratory Medicine Commentaries: COVID-19-related ARDS: one disease, two trajectories, and several unanswered questions – The Lancet Respiratory Medicine Respiratory Subphenotypes of COVID-19-Related ARDS – ICU Management & Practice   Commentary on Twitter NEW—At baseline, #COVID19-related #ARDS […]

The post Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts. appeared first on Links Medicus.

RCT: Early treatment of Covid-19 with SARS-CoV-2 neutralizing antibody Sotrovimab is associated with reduced risk of hospitalization.

Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab – New England Journal of Medicine   Commentary on Twitter In this phase 3 trial, sotrovimab or placebo was administered to outpatients within 5 days after the onset of #COVID19 symptoms. Patients receiving sotrovimab had a lower incidence of hospitalization for any reason. #IDTwitter https://t.co/4VcgoK3xac pic.twitter.com/W82v3jNRmB […]

The post RCT: Early treatment of Covid-19 with SARS-CoV-2 neutralizing antibody Sotrovimab is associated with reduced risk of hospitalization. appeared first on Links Medicus.

RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19.

Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial – The Lancet Global Health Commentaries: Expert reaction to study looking at fluvoxamine as a COVID-19 treatment in high-risk outpatients with early-diagnosed COVID-19 – Science Media Centre The TOGETHER Trial: COVID-19 and […]

The post RCT: Early treatment with fluvoxamine reduced the risk of emergency care and hospitalization among patients with COVID-19. appeared first on Links Medicus.

COVID super-immunity: one of the pandemic’s great puzzles – “People who have previously recovered from COVID-19 have a stronger immune response after being vaccinated than those who have never been infected. Scientists are trying to find out why”.

Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”.

Mix-and-match COVID vaccines ace the effectiveness test – Nature Related: Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden. Should You Mix and Match Your Booster Shot? Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no […]

The post Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”. appeared first on Links Medicus.

Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination.

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature Related: Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden. Should You Mix and Match Your Booster Shot? Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no […]

The post Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination. appeared first on Links Medicus.