[Press release – not published yet] RCT: Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR study.
Pfizer’s novel Covid-19 oral antiviral treatment candidate reduced risk of hospitalization or death by 89% in interim analysis of phase 2/3 EPIC-HR Study Commentaries: Expert reaction to press release from Pfizer giving interim analysis of their Phase 2/3 EPIC-HR study of PAXLOVID™ in non-hospitalized high-risk adults with COVID-19 – Science Media Centre Pfizer’s Good News […]
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The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first.
The U.K. approves Merck’s COVID-19 antiviral pill, calling it a world first – NPR Related: Merck to allow other nations to produce new COVID-19 antiviral. Video: Merck’s Covid pill could transform treatment. Here’s how it works. How antiviral pill Molnupiravir shot ahead in the COVID drug hunt. What we know — and don’t know — […]
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Review: SARS-CoV-2 indoor air transmission is a threat that can be addressed with science.
SARS-CoV-2 indoor air transmission is a threat that can be addressed with science – Proceedings of the National Academies of Sciences Related: Ten scientific reasons in support of airborne transmission of SARS-CoV-2 Editorial: Covid-19 has redefined airborne transmission Covid-19: What do we know about airborne transmission of SARS-CoV-2? Real-world data show that filters clean COVID-causing […]
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Study compares the decline in effectiveness for Moderna, Pfizer, and Janssen vaccines and consequences for mortality.
Original study: SARS-CoV-2 vaccine protection and deaths among US veterans during 2021 – Science News release: Breakthrough Infection Study Compares Decline in Vaccine Effectiveness and Consequences for Mortality – Public Health Institute Commentary on Twitter A new study of more than 780,000 United States Veterans shows that, although vaccination remains protective against #SARSCoV2 infection, […]
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M-A: Zinc might help to stave off respiratory infection symptoms and cut illness duration – “But quality of evidence variable, and no clarity on optimal formulation or dose”.
News Release: Zinc might help to stave off respiratory infection symptoms and cut illness duration – BMJ Original Study: Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials – BMJ Open Commentary on Twitter A zinc supplement might help […]
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The USPSTF draft statement recommends against screening for chronic obstructive pulmonary disease in asymptomatic adults.
Chronic Obstructive Pulmonary Disease: Screening – U.S. Preventive Services Task Force Commentary: USPSTF Still Advises Against COPD Screening for Asymptomatic Adults – HealthDay
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ASH Guideline issued a conditional recommendation against routine use of outpatient anticoagulant prophylaxis in patients with COVID-19 being discharged from the hospital.
American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: July 2021 update on post-discharge thromboprophylaxis – Blood Advances
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CDC Guidance: Immunocompromised may need a fourth Covid-19 shot.
Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Approved or Authorized in the United States – Centers for Disease Control and Prevention Commentaries: Immunocompromised may need a fourth Covid-19 shot, CDC says – CNN Some immunocompromised people can receive a 4th Covid shot, CDC says – NBC News
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Observational study showed J&J single shot vaccine had an effectiveness of 74% against symptomatic Covid-19.
Analysis of the Effectiveness of the Ad26.COV2.S Adenoviral Vector Vaccine for Preventing COVID-19 – JAMA Network Open Commentaries: Single-Dose Ad26.COV2.S Vaccine—Room for Improvement – JAMA Network Open Real-world study shows J&J COVID-19 vaccine 74% effective – CIDRAP Related: J&J COVID-19 Vaccine: FDA recommends booster shot for all adults aged 18 and older at least two […]
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RCT: Among children with community-acquired pneumonia discharged within 48 hours from the ED or hospital, lower-dose outpatient oral amoxicillin was noninferior to a higher dose, and a 3-day duration course was noninferior to 7 days.
Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA (free for a limited period) Related: RCT: 5 days of high-dose amoxicillin therapy noninferior to 10 days for the treatment of pediatric community-acquired pneumonia Randomized Trial: Amoxicillin for 3 Days […]
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