M-A | Efficacy of Doxycycline for mild-to-moderate community-acquired pneumonia in adults.
Efficacy of Doxycycline for Mild-to-moderate Community-acquired Pneumonia in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials – Clinical Infectious Diseases (link to abstract – $ for full-text) Commentary on Twitter ?⚡⚡Systematic Review and Meta-analysis of Randomized Controlled Trials @CIDJournal Efficacy of Doxycycline for Mild-to-moderate CAP in AdultsThe efficacy of doxycycline was comparable […]
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RCT | Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension.
Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study – The Lancet Respiratory Medicine (link to abstract – $ for full-text) Commentary on Twitter NEW—Pulmonary vascular resistance reduction was more pronounced with balloon pulmonary angioplasty (BPA) […]
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RCT | Temporary transvenous phrenic nerve stimulation does not benefit difficult-to-wean patients in the ICU.
Randomized Clinical Study of Temporary Transvenous Phrenic Nerve Stimulation in Difficult-to-Wean Patients – American Journal of Respiratory and Critical Care Medicine Editorial: Transvenous Phrenic Nerve Stimulation: A Novel Therapy Gathering Pace – American Journal of Respiratory and Critical Care Medicine
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Systematic Review | Impact of low‐dose computed tomography screening on lung cancer‐related mortality.
Impact of low‐dose computed tomography (LDCT) screening on lung cancer‐related mortality – Cochrane Library Summary: Impact of computed tomography (CT) on lung cancer screening – Cochrane Library Related: Association of computed tomography screening with lung cancer stage shift and survival in the United States: quasi-experimental study – The BMJ Screening for Lung Cancer: CHEST Guideline […]
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RCT | Effectiveness of Varenicline and Cytisine for alcohol use reduction among people with HIV and substance use.
Effectiveness of Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use: A Randomized Clinical Trial – JAMA Network Open Commentary: Varenicline and cytisine not more efficacious than nicotine to treat risky drinking and smoking, study says – News Medical / Vanderbilt University Medical Center Commentary on Twitter In this […]
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Systematic Review | Smoking cessation for secondary prevention of cardiovascular disease.
Smoking cessation for secondary prevention of cardiovascular disease – Cochrane Library Summary: Does stopping smoking make people with heart disease less likely to have another heart attack? – Cochrane Library
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Systematic Review | Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism.
Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute pulmonary embolism – Cochrane Library Summary: Minimally invasive treatments to dissolve blood clots in the lungs (acute pulmonary embolism) – Cochrane Library
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Systematic Review | Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis.
Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis – Cochrane Library Summary: Inhaling antibiotics to treat temporary worsening of lung infection in people with cystic fibrosis – Cochrane Library
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Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions.
Extracorporeal carbon dioxide removal for acute respiratory failure: a review of potential indications, clinical practice and open research questions – Intensive Care Medicine Commentary on Twitter Extracorporeal carbon dioxide removal #ECCO2r: to date indications & risk-to-beneft ratio of this technique should now be carefully evaluated using structured national or international registries and large randomized […]
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RCT | Tobramycin inhalation solution is effective in adults with bronchiectasis with pseudomonas aeruginosa infection.
A Double-blind Randomized Placebo-controlled Phase-3 Trial of Tobramycin Inhalation Solution in Adults with Bronchiectasis with Pseudomonas aeruginosa Infection – CHEST Commentary: Tobramycin Tames Infection in Bronchiectasis – Medscape (free registration required) Related Study: Testing the effects of combining azithromycin with inhaled tobramycin for P. aeruginosa in cystic fibrosis: a randomised, controlled clinical trial – Thorax
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