RCT | Mepolizumab for urban children with exacerbation-prone eosinophilic asthma.
Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial – The Lancet (link to abstract – $ for full-text) Commentary: Mepolizumab Cuts Exacerbations in Children With Severe Asthma – HealthDay
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ATS/ERS/JRS/ALAT Research Statement | Syndrome of combined pulmonary fibrosis and emphysema.
Syndrome of Combined Pulmonary Fibrosis and Emphysema: An Official ATS/ERS/JRS/ALAT Research Statement – American Journal of Respiratory and Critical Care Medicine Commentary on Twitter In this international statement, we propose a research definition of CPFE (for research purposes), +classification criteria of CPFE clinical syndrome for clinicians. Hopefully both will help the field move forward.Thanks […]
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Guideline Summary | Recommendations for the outpatient drug treatment of patients with COVID-19.
Recommendations for the Outpatient Drug Treatment of Patients With COVID-19 – Deutsches Ärzteblatt International
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RCT | Stopping vs. continuing long-term mepolizumab treatment in severe eosinophilic asthma.
Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study) – European Respiratory Journal Commentary: Exacerbations Increased After Discontinuing Long-term Use of Mepolizumab for Severe Eosinophilic Asthma – Consultant 360 Commentary on Twitter This randomised study demonstrates increased exacerbation risk and a decrease in asthma control in patients with severe eosinophilic asthma who stop […]
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Updated systematic review and critical appraisal: prediction models for diagnosis and prognosis of covid-19.
Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal – The BMJ Commentary: Update to living systematic review on prediction models for diagnosis and prognosis of covid-19 – The BMJ Commentary on Twitter NEW update in @bmj_latest 606 prognostic models for #COVID19 identified – 29 had low risk of bias, […]
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Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients.
Association of COVID-19 vs Influenza With Risk of Arterial and Venous Thrombotic Events Among Hospitalized Patients – JAMA Commentary: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP News Release: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News Commentary on Twitter The risk […]
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Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19.
Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19 – JAMA Internal Medicine Commentary on Twitter Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research — JAMA Internal Medicine […]
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Systematic Review | Pulmonary rehabilitation versus usual care for adults with asthma.
Pulmonary rehabilitation versus usual care for adults with asthma – Cochrane Library Summary: What are the benefits of supervised programmes of exercise and education (known as pulmonary rehabilitation) compared with usual care for adults with asthma? – Cochrane Library Commentary on Twitter Very excited to see our new @CochraneAirways review in print! A modest […]
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Meta-analysis of randomized trials | Intensive vs. short face-to-face smoking cessation interventions.
Intensive versus short face-to-face smoking cessation interventions: a meta-analysis – European Respiratory Review
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#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma.
Oxygen Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text) News Release: Restrictive oxygenation in post cardiac arrest patients is not harmful – European Society of Cardiology Commentary on Twitter BOX Oxygen: This RCT found no difference in the rate of death or […]
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