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RCT | Stopping vs. continuing long-term mepolizumab treatment in severe eosinophilic asthma.

Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study) – European Respiratory Journal Commentary: Exacerbations Increased After Discontinuing Long-term Use of Mepolizumab for Severe Eosinophilic Asthma – Consultant 360   Commentary on Twitter This randomised study demonstrates increased exacerbation risk and a decrease in asthma control in patients with severe eosinophilic asthma who stop […]

The post RCT | Stopping vs. continuing long-term mepolizumab treatment in severe eosinophilic asthma. appeared first on Links Medicus.

Updated systematic review and critical appraisal: prediction models for diagnosis and prognosis of covid-19.

Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal – The BMJ Commentary: Update to living systematic review on prediction models for diagnosis and prognosis of covid-19 – The BMJ   Commentary on Twitter NEW update in @bmj_latest 606 prognostic models for #COVID19 identified – 29 had low risk of bias, […]

The post Updated systematic review and critical appraisal: prediction models for diagnosis and prognosis of covid-19. appeared first on Links Medicus.

Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients.

Association of COVID-19 vs Influenza With Risk of Arterial and Venous Thrombotic Events Among Hospitalized Patients – JAMA Commentary: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP News Release: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News   Commentary on Twitter The risk […]

The post Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients. appeared first on Links Medicus.

Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19.

Clinical and Genetic Risk Factors for Acute Incident Venous Thromboembolism in Ambulatory Patients With COVID-19 – JAMA Internal Medicine   Commentary on Twitter Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research — JAMA Internal Medicine […]

The post Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19. appeared first on Links Medicus.

Systematic Review | Pulmonary rehabilitation versus usual care for adults with asthma.

Pulmonary rehabilitation versus usual care for adults with asthma – Cochrane Library Summary: What are the benefits of supervised programmes of exercise and education (known as pulmonary rehabilitation) compared with usual care for adults with asthma? – Cochrane Library   Commentary on Twitter Very excited to see our new @CochraneAirways review in print! A modest […]

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Meta-analysis of randomized trials | Intensive vs. short face-to-face smoking cessation interventions.

Intensive versus short face-to-face smoking cessation interventions: a meta-analysis – European Respiratory Review  

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#ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma.

Oxygen Targets in Comatose Survivors of Cardiac Arrest – New England Journal of Medicine (link to abstract – $ for full-text) News Release: Restrictive oxygenation in post cardiac arrest patients is not harmful – European Society of Cardiology   Commentary on Twitter BOX Oxygen: This RCT found no difference in the rate of death or […]

The post #ESCCongress – RCT | In comatose survivors of out-of-hospital cardiac arrest, a restrictive vs. a liberal oxygenation strategy resulted in similar incidences of death, severe disability, and coma. appeared first on Links Medicus.

#ESCCongress | 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: Developed by the task force for the diagnosis and treatment of pulmonary hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). Endorsed by the International Society for Heart and Lung Transplantation (ISHLT) and the European Reference Network on rare […]

The post #ESCCongress | 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. appeared first on Links Medicus.

M-A | Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19.

Beneficial and harmful effects of monoclonal antibodies for the treatment and prophylaxis of COVID-19: a systematic review and meta-analysis of randomized controlled trials – American Journal of Medicine  

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M-A | Antiviral drug treatment for nonsevere COVID-19.

Antiviral drug treatment for nonsevere COVID-19: a systematic review and network meta-analysis – Canadian Medical Association Journal News Release: Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths – Canadian Medical Association Journal Commentary: COVID-19 antivirals may cut risk of hospitalization, death – CIDRAP  

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