RCT | Dexamethasone is not effective for the treatment of dyspnea in patients with cancer and increases the risk of adverse events.
Effect of dexamethasone on dyspnoea in patients with cancer (ABCD): a parallel-group, double-blind, randomised, controlled trial – The Lancet Oncology (free for a limited period) Commentary on Twitter Our phase III randomized study, published in Lancet Oncology today, showed high-dose steroid didn’t improve SOB and should not be used routinely in pts with lung […]
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M-A of randomized trials | In patients hospitalized with community-acquired pneumonia, corticosteroids reduce the need for mechanical ventilation without significant effects on mortality, treatment failure, or adverse events.
Effect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: A systematic review, meta-analysis, and meta-regression of randomized control trials – CHEST Journal (link to abstract – $ for full-text) Related: Corticosteroids for CAP, influenza and COVID-19: when, how and benefits or harm? – European Respiratory Review
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The Lancet Commission | Towards the elimination of chronic obstructive pulmonary disease.
Homepage: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission – The Lancet Commission: Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission Editorial: COPD: from an end-stage disease to lifelong lung health Invited Commentary: Classification of COPD: fostering prevention and precision medicine in the Lancet Commission on COPD Commentary: Proposed classification of COPD according […]
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The Lancet Commission on lessons for the future from the COVID-19 pandemic – “a massive global failure.”
Homepage: The Lancet COVID-19 Commission The Lancet Commission on lessons for the future from the COVID-19 pandemic Editorial: COVID-19: the case for prosociality News Release: New report details “massive global failures” of COVID-19 response, calls for improved multilateral cooperation to end pandemic and effectively manage future global health threats – The Lancet Infographic: COVID-19 response: a massive global failure […]
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ISHLT consensus statement | Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery.
ISHLT consensus statement: Perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery – the Journal of Heart and Lung Transplantation Related Guideline: Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement – British Journal of Anaesthesia
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Pulmonary artery denervation for pulmonary arterial hypertension: a sham-controlled randomized trial.
Pulmonary Artery Denervation for Pulmonary Arterial Hypertension: A Sham-Controlled Randomized Trial – JACC: Cardiovascular Interventions Commentaries: Pulmonary Artery Denervation in Idiopathic PAH Ups 6-Minute Walk Test – TCTMD Pulmonary Artery Denervation for Pulmonary Arterial Hypertension – PADN-CFDA – American College of Cardiology Commentary on Twitter #TCT2022 #JACCINT LBCT SimPub: PADN-CFDA trial included 128 pts […]
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Extracorporeal membrane oxygenation during respiratory pandemics: past, present, and future.
Extracorporeal Membrane Oxygenation during Respiratory Pandemics: Past, Present, and Future – American Journal of Respiratory and Critical Care Medicine
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Two large clinical trials showed Vitamin D supplements do not reduce the risk of Covid-19.
Study 1: Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: phase 3 randomised controlled trial (CORONAVIT) – The BMJ Study 2: Prevention of covid-19 and other acute respiratory infections with cod liver oil supplementation, a low dose vitamin D supplement: quadruple blinded, randomised […]
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Brief Review | Physiology of extracorporeal CO2 removal.
Physiology of extracorporeal CO2 removal – Intensive Care Medicine
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Cohort Study | Electrocardiographic findings associated with early clinical deterioration in acute pulmonary embolism.
Electrocardiographic findings associated with early clinical deterioration in acute pulmonary embolism – Academic Emergency Medicine
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