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Randomized trial: Tocilizumab does not improve outcomes for patients hospitalized with Covid-19

Efficacy of Tocilizumab in Patients Hospitalized with Covid-19 – New England Journal of Medicine Commentary: Tocilizumab doesn’t ease symptoms or prevent death in moderately ill COVID-19 inpatients – Massachusetts General Hospital  

The post Randomized trial: Tocilizumab does not improve outcomes for patients hospitalized with Covid-19 appeared first on Links Medicus.

Podcast: Approach to shortness of breath

#236 Physical Exam Series: Approach to Shortness of Breath – The Curbsiders Internal Medicine Podcast  

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Studies point to big drop in COVID-19 death rates

Studies Point To Big Drop In COVID-19 Death Rates – NPR  

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Studies offer little hope for Tocilizumab in treating COVID

Studies offer little hope for tocilizumab in treating COVID – CIDRAP See studies: Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19 – JAMA Internal Medicine AND Effect of Tocilizumab vs Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia: A Randomized Clinical Trial – JAMA Internal Medicine […]

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Meta-analysis: The association of D-dimers with mortality, intensive care unit admission or ARDS in patients hospitalized with COVID-19

The association of D-dimers with mortality, intensive care unit admission or acute respiratory distress syndrome in patients hospitalized with coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis – Heart & Lung  

The post Meta-analysis: The association of D-dimers with mortality, intensive care unit admission or ARDS in patients hospitalized with COVID-19 appeared first on Links Medicus.

Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s?

Antimicrobial stewardship in ICUs during the COVID-19 pandemic: back to the 90s? – Intensive Care Medicine   Commentary on Twitter Side effect of #COVID19 surge: ignoring well established strategies➡️ limit ABTs exposure vs resistances: MV/long #ICU stay➡️ avoid toxicity: antivirals/antibiotics can have severe adverse effects/interactions➡️ high mortality: improving outcome crucial https://t.co/FN3LtKKlsr pic.twitter.com/7KGbIOH3Uf — Intens Care […]

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Herd immunity and implications for SARS-CoV-2 control

Herd Immunity and Implications for SARS-CoV-2 Control – JAMA Author Interview: Can We Count on Herd Immunity to Control COVID-19? – JAMA Patient Page: What Is Herd Immunity? – JAMA   Commentary on Twitter Herd immunity is real. It may be inevitable given our poor handling of COVID-19 and nature of the virus. But to […]

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[Preprint] Multi-organ impairment in low-risk individuals with long COVID

Multi-organ impairment in low-risk individuals with long COVID – medRxiv Related study (preprint): Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services – medRxiv   Commentary on Twitter "In a young, low-risk population with ongoing symptoms, almost 70% of individuals have impairment in 1 or more organs […]

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Cytokine elevation in severe and critical COVID-19: A rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes

Cytokine elevation in severe and critical COVID-19: a rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes – The Lancet Respiratory Medicine   Commentary on Twitter The cytokine storm of severe #COVID19 and how it differs from ARDS, sepsis, and CAR-T cytokine release syndrome. Best review to date on this ★Today @LancetRespirMed https://t.co/BOUjvIOWLi @danleisman […]

The post Cytokine elevation in severe and critical COVID-19: A rapid systematic review, meta-analysis, and comparison with other inflammatory syndromes appeared first on Links Medicus.

Answering key questions about COVID-19 vaccines

Answering Key Questions About COVID-19 Vaccines – JAMA   Commentary on Twitter Many individuals are hesitant about receiving #COVID19 vaccines. It is critical that clinicians stay well informed about emerging data so that they can help patients make sound decisions https://t.co/1QDwOKuDqc @JesseGoodmanMD @ImmunizeOrg @pharmacists — JAMA (@JAMA_current) October 16, 2020  

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