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Nested Case-Control Study: Increased risk of major bleeding in atrial fibrillation patients with concomitant SSRI and oral anticoagulant use

Study Design and Population This nested case-control study investigated the association between the concomitant use of selective serotonin reuptake inhibitors (SSRIs) and oral anticoagulants (OACs) on the risk of major bleeding among patients with atrial fibrillation. Conducted within the UK’s Clinical Practice Research Datalink, the study included 42,190 cases of major bleeding matched to 1,156,641 […]

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Diaphragmatic function in cardiovascular disease: JACC review topic of the week.

Diaphragmatic Function in Cardiovascular Disease: JACC Review Topic of the Week – Journal of the American College of Cardiology  

The post Diaphragmatic function in cardiovascular disease: JACC review topic of the week. appeared first on Links Medicus.

RCT | In critically ill patients receiving MV, there was no difference in outcomes between different O2 saturation targets.

Oxygen-Saturation Targets for Critically Ill Adults Receiving Mechanical Ventilation – New England Journal of Medicine (link to abstract – $ for full-text) News Release: Study finds that the most common oxygen saturation targets for hospitalized patients appear equally safe and effective – Vanderbilt University Medical Center Related: Effect of Low-Normal vs High-Normal Oxygenation Targets on […]

The post RCT | In critically ill patients receiving MV, there was no difference in outcomes between different O2 saturation targets. appeared first on Links Medicus.

RCT | Ivermectin does not improve time to recovery in outpatients with mild to moderate COVID-19.

Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial – JAMA Commentary: Ivermectin doesn’t speed time to recovery from nonsevere COVID – CIDRAP   Commentary on Twitter Study findings do not support the use of #ivermectin in outpatients with mild to moderate #COVID19. […]

The post RCT | Ivermectin does not improve time to recovery in outpatients with mild to moderate COVID-19. appeared first on Links Medicus.

Podcast | Chronic Obstructive Pulmonary Disease (COPD) Update.

#356 Chronic Obstructive Pulmonary Disease (COPD) Update with Dr. Antonio Anzueto – The Curbsiders  

The post Podcast | Chronic Obstructive Pulmonary Disease (COPD) Update. appeared first on Links Medicus.

M-A | Higher vs. lower oxygenation strategies in the general intensive care unit population.

Higher versus lower oxygenation strategies in the general intensive care unit population: A systematic review, meta-analysis and meta-regression of randomized controlled trials – Journal of Critical Care Related: Oxygen targets – Intensive Care Medicine (if the link is paywalled, try this one) Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: […]

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RCT | Riociguat improved hemodynamics but increased dropouts in pulmonary hypertension and HFpEF.

Riociguat in pulmonary hypertension and heart failure with preserved ejection fraction: the haemoDYNAMIC trial – European Heart Journal   Commentary on Twitter Riociguat in pulmonary hypertension and heart failure with preserved ejection fraction: results of randomized, double-blind, placebo-controlled, multicentre trial out.https://t.co/FYmorikQR5#HFpEF #HF #cardiotwitter @ESC_Journals @escardio pic.twitter.com/4sSeYt7Adq — EHJ Editor-in-Chief (@ehj_ed) October 7, 2022 Under a […]

The post RCT | Riociguat improved hemodynamics but increased dropouts in pulmonary hypertension and HFpEF. appeared first on Links Medicus.

Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications.

Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications – Annals of Intensive Care  

The post Extracorporeal membrane oxygenation for cardiogenic shock: a meta-analysis of mortality and complications. appeared first on Links Medicus.

Development of a symptom-based tool for screening of children at high risk of preschool asthma.

Development of a Symptom-Based Tool for Screening of Children at High Risk of Preschool Asthma – JAMA Network Open News Release: Simple new tool allows primary caregivers to detect young kids at high risk of asthma – McMaster University   Commentary on Twitter The CHILDhood Asthma Risk Tool #CHART applied at 3 years of age […]

The post Development of a symptom-based tool for screening of children at high risk of preschool asthma. appeared first on Links Medicus.

Estimated global proportions of persistent fatigue, cognitive, and respiratory symptoms following symptomatic COVID-19.

Estimated Global Proportions of Individuals With Persistent Fatigue, Cognitive, and Respiratory Symptom Clusters Following Symptomatic COVID-19 in 2020 and 2021 – JAMA Commentaries: Women And Hospitalized Patients More Prone To Long Covid, Study Finds – Forbes Nearly two-thirds of long COVID patients are female, global study finds – UPI   Commentary on Twitter A new […]

The post Estimated global proportions of persistent fatigue, cognitive, and respiratory symptoms following symptomatic COVID-19. appeared first on Links Medicus.