Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies.
Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies – ESMO Open Commentaries: Prompt recognition and treatment found effective for lung disease in patients who received new drug for advanced cancer – The Mount Sinai Health System Trastuzumab deruxtecan-related ILD/pneumonitis characterized – medwire News Related: Trastuzumab Deruxtecan-Induced Interstitial Lung […]
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RCT | Metformin, Ivermectin, and Fluvoxamine are not beneficial for obese outpatients with Covid-19.
Randomized Trial of Metformin, Ivermectin, and Fluvoxamine for Covid-19 – New England Journal of Medicine Editorial: Time to Stop Using Ineffective Covid-19 Drugs – New England Journal of Medicine Commentary on Twitter In this trial involving overweight or obese outpatients with Covid-19, investigators found that none of three repurposed drugs (metformin, ivermectin, and fluvoxamine) […]
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NICE Guideline | Pneumonia in adults: diagnosis and management.
Pneumonia in adults: diagnosis and management – National Institute for Health and Care Excellence Related Guidelines: Pneumonia (community-acquired): antimicrobial prescribing Pneumonia (hospital-acquired): antimicrobial prescribing Diagnosis and Treatment of Adults with Community-acquired Pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America – American Journal of Respiratory and Critical […]
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RCT | The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis.
The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text) Commentary: Inhaled hypertonic saline improves structural airway changes in children with cystic fibrosis – Healio (free registration required)
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Systematic Review | Antiplatelet agents for the treatment of deep venous thrombosis.
Antiplatelet agents for the treatment of deep venous thrombosis – Cochrane Library Summary: Aspirin and similar drugs for the treatment of deep vein thrombosis (DVT) – Cochrane Library
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[PREPRINT] RCT | Inhaled fluticasone not beneficial for outpatients with Covid-19.
Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv News Release: Study finds no benefit to taking fluticasone furoate for COVID-19 symptoms – Duke Clinical Research Institute Commentary: Asthma Drug Fluticasone Fails as Potential COVID-19 Treatment – HealthDay
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Retrospective Cohort Study | Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old.
Effectiveness of a fourth dose of mRNA COVID-19 vaccine against all-cause mortality in long-term care facility residents and in the oldest old: A nationwide, retrospective cohort study in Sweden – The Lancet Regional Health Europe Related: Effectiveness of a fourth dose of covid-19 mRNA vaccine against the omicron variant among long term care residents in […]
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Guideline Synopsis | Therapy for mild to moderate asthma.
Therapy for Mild to Moderate Asthma – JAMA (free for a limited period) Original Guideline: 2022 GINA Report, Global Strategy for Asthma Management and Prevention Related: Global Initiative for Asthma (GINA) Strategy 2021 – Executive summary and rationale for key changes – European Respiratory Journal
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M-A | Risk factors for asthma exacerbations during pregnancy.
Risk factors for asthma exacerbations during pregnancy: a systematic review and meta-analysis – European Respiratory Review
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RCT | Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD.
Using a smartphone application maintains physical activity following pulmonary rehabilitation in patients with COPD: a randomised controlled trial – Thorax
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