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RCT | P2Y12 inhibitors don’t improve outcomes in critically ill COVID-19 patients

Effect of P2Y12 Inhibitors on Organ Support–Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial – JAMA Network Open See also: Visual Abstract  

The post RCT | P2Y12 inhibitors don’t improve outcomes in critically ill COVID-19 patients appeared first on Links Medicus.

Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care

Implementation of point-of-care testing of C-reactive protein concentrations to improve antibiotic targeting in respiratory illness in Vietnamese primary care: a pragmatic cluster-randomised controlled trial – The Lancet Infectious Diseases Commentary: Use of CRP testing reduced antibiotics for respiratory infections, trial finds – CIDRAP  

The post Cluster RCT | Point-of-care CRP testing cuts antibiotic prescriptions in respiratory illnesses in primary care appeared first on Links Medicus.

M-A | Noninvasive ventilation in patients with acute hypoxemic respiratory failure

Noninvasive ventilation in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis of randomized controlled trials – Scientific Reports  

The post M-A | Noninvasive ventilation in patients with acute hypoxemic respiratory failure appeared first on Links Medicus.

RCT | Dupilumab improves lung function and reduces exacerbations in COPD patients with elevated eosinophils

Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts – New England Journal of Medicine (link to abstract – $ for full-text) Commentary: Dupilumab Improves Outcomes for COPD, Type 2 Inflammation in Randomized Trial – HCP Live   Commentary on Twitter Presented at #ATS2023: In the BOREAS trial, dupilumab resulted in a lower […]

The post RCT | Dupilumab improves lung function and reduces exacerbations in COPD patients with elevated eosinophils appeared first on Links Medicus.

Manual prone positioning in adults: reducing the risk of harm through evidence-based practices

Manual Prone Positioning in Adults: Reducing the Risk of Harm Through Evidence-Based Practices – Critical Care Nurse News Release: New guidance on manual prone positioning for patients with ARDS – American Association of Critical-Care Nurses  

The post Manual prone positioning in adults: reducing the risk of harm through evidence-based practices appeared first on Links Medicus.

Review | Interventional therapies for pulmonary embolism

Interventional therapies for pulmonary embolism – Nature Reviews Cardiology (if the link is paywalled, try this one)   Commentary on Twitter In our latest Review, @FelixMahfoud et al. discuss interventional therapies for pulmonary embolism. Check it out here: https://t.co/sBDfnZno1q pic.twitter.com/XNLclSbjmr — Nature Reviews Cardiology (@NatRevCardiol) May 14, 2023  

The post Review | Interventional therapies for pulmonary embolism appeared first on Links Medicus.

M-A | Residual respiratory disability after successful treatment of pulmonary tuberculosis

Residual respiratory disability after successful treatment of pulmonary tuberculosis: a systematic review and meta-analysis – eClinicalMedicine  

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Systematic Review | Bupropion and nortriptyline: an assessment of their effectiveness in smoking cessation

Antidepressants for smoking cessation – Cochrane Library  

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RCT | Noninferiority shown between DOACs and LMWH for recurrent VTE prevention in cancer patients

Summary: This unblinded, pragmatic, noninferiority randomized clinical trial aimed to assess the efficacy of direct oral anticoagulants (DOACs) against low-molecular-weight heparin (LMWH) in preventing recurrent venous thromboembolism (VTE) in patients with cancer. The study included 671 patients from 67 oncology centers, with a new clinical or radiological diagnosis of VTE. Participants were randomly assigned to […]

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Review | Hemodynamic and respiratory support in pulmonary embolism

Hemodynamic and respiratory support in pulmonary embolism: a narrative review – Frontiers in Medicine  

The post Review | Hemodynamic and respiratory support in pulmonary embolism appeared first on Links Medicus.

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