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[Not published yet] Observational study in Indonesia finds China’s Sinovac COVID-19 vaccine (CoronaVac) was 98% effective at preventing death and 96% effective at preventing hospitalization in healthcare workers

RCT: Among adults with idiopathic pulmonary fibrosis, antimicrobial therapy with co-trimoxazole or doxycycline is not associated with improved outcomes.

Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial – JAMA (free for a limited period)   Commentary on Twitter Among adults with idiopathic pulmonary fibrosis, addition of co-trimoxazole or doxycycline compared with usual care did not significantly improve the time to nonrespiratory hospitalization […]

The post RCT: Among adults with idiopathic pulmonary fibrosis, antimicrobial therapy with co-trimoxazole or doxycycline is not associated with improved outcomes. appeared first on Links Medicus.

Coronavirus variants are spreading in India — what scientists know so far.

Coronavirus variants are spreading in India — what scientists know so far – Nature  

The post Coronavirus variants are spreading in India — what scientists know so far. appeared first on Links Medicus.

[Preprint] Meta-analysis of risk of vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1-S recombinant vaccine – Overall risk is 1 in 139,000; for age 65 and over, about 1 in 1,000,000; for age under 55, between 1 in 20,000 to 60,000.

Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased.

Post-acute effects of SARS-CoV-2 infection in individuals not requiring hospital admission: a Danish population-based cohort study – The Lancet Infectious Diseases Commentaries: Non-hospitalized COVID-19 patients: Low-risk of serious long-term effects, but more visits to doctor – The Lancet AND Any COVID-19 Infection Raises Odds for Lingering Symptoms, Study Finds – HealthDay AND Those with mild […]

The post Population-based cohort study: Non-hospitalized COVID-19 patients have low-risk of serious long-term effects, but visits to general practitioners and outpatient hospital visits are increased. appeared first on Links Medicus.

Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas high

Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – American College of Physicians Original study: Factors Associated With Risk for Care Escalation Among Patients With COVID-19 Receiving Home-Based Hospital Care – Annals of Internal Medicine Related: Pandemic Boosts an Old Idea—Bringing Acute Care to the Patient  

The post Most COVID-19 patients receiving home-based hospital care did not require escalation to traditional hospital setting – Approximately 1 in 5 were admitted within 14 days. Higher oxygen saturation was associated with decreased odds of transfer, whereas higher comorbidity burden was associated with increased risk. appeared first on Links Medicus.

M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality.

Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis – Scientific Reports Commentary: People living with HIV more likely to get sick with, die from COVID-19 – Penn State Related: Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a […]

The post M-A: Epidemiology and outcomes of COVID-19 in HIV-infected individuals – HIV is a significant risk factor for acquiring SARS-CoV-2 infection and is associated with a higher risk of mortality. appeared first on Links Medicus.

Pfizer COVID-19 shot expanded to US children as young as 12.

Pfizer COVID-19 shot expanded to US children as young as 12 – Associated Press Counterpoint: Covid vaccines for children should not get emergency use authorization – The BMJ Opinion Commentaries: Covid-19: FDA authorises Pfizer vaccine for children 12-15 – The BMJ AND Expert reaction to U.S. FDA authorising Pfizer-BioNTech COVID-19 vaccine for emergency use in […]

The post Pfizer COVID-19 shot expanded to US children as young as 12. appeared first on Links Medicus.

Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%).

Eight out of ten people hospitalized with COVID-19 develop neurological problems – University of Pittsburgh Original study: Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19—A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium – JAMA Network Open Related: [Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 […]

The post Eight out of ten people hospitalized with COVID-19 develop neurological problems – the most common self-reported symptoms included headache (37%) and anosmia or ageusia (26%). appeared first on Links Medicus.

Mucormycosis: The ‘black fungus’ maiming Covid patients in India

Mucormycosis: The ‘black fungus’ maiming Covid patients in India – BBC See also: Potentially fatal ‘black fungus’ infections on the rise in India’s COVID-19 patients – LiveScience AND A potentially fatal fungal infection is cropping up among India’s Covid patients. – The New York Times AND WHO says virus strain in India a ‘variant of […]

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