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Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech reduced the rates of confirmed Covid-19 and severe illness compared to a two-dose regimen.

Protection against Covid-19 by BNT162b2 Booster across Age Groups – New England Journal of Medicine Editorial: Booster Doses and Prioritizing Lives Saved  

The post Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech reduced the rates of confirmed Covid-19 and severe illness compared to a two-dose regimen. appeared first on Links Medicus.

Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine had 90% effectiveness at preventing death due to Covid-19 compared to a two-dose regimen.

BNT162b2 Vaccine Booster and Mortality Due to Covid-19 – New England Journal of Medicine Editorial: Booster Doses and Prioritizing Lives Saved  

The post Large observational study in Israel showed a third dose (booster) of the Pfizer–BioNTech vaccine had 90% effectiveness at preventing death due to Covid-19 compared to a two-dose regimen. appeared first on Links Medicus.

ESC Position Paper: Optimal follow-up after acute pulmonary embolism.

Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society – European Heart Journal   Commentary on Twitter Do you […]

The post ESC Position Paper: Optimal follow-up after acute pulmonary embolism. appeared first on Links Medicus.

Beyond Omicron: what’s next for COVID’s viral evolution.

Beyond Omicron: what’s next for COVID’s viral evolution – Nature  

The post Beyond Omicron: what’s next for COVID’s viral evolution. appeared first on Links Medicus.

Video | COVID-19 Update: Omicron Variant.

COVID-19 Update: Omicron Variant – JAMA  

The post Video | COVID-19 Update: Omicron Variant. appeared first on Links Medicus.

Phase 2 RCT: Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule.

Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials – The Lancet Infectious Diseases Invited Commentary: Booster doses for inactivated COVID-19 vaccines: if, when, and for whom – The Lancet Infectious Diseases  

The post Phase 2 RCT: Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule. appeared first on Links Medicus.

RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy.

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial – JAMA Related: Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of […]

The post RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy. appeared first on Links Medicus.

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants.

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants – STAT Original Study: SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection – medRxiv   Commentary from the author on Twitter (thread – click for more) We have completed our […]

The post A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants. appeared first on Links Medicus.

WHO recommends against the use of convalescent plasma to treat COVID-19.

News Release: WHO recommends against the use of convalescent plasma to treat COVID-19 – World Health Organization See Guidance: WHO’s living guidelines on COVID-19 therapeutics Infographic: A living WHO guideline on drugs for covid-19 – The BMJ   Commentary on Twitter (thread – click for more) Convalescent plasma is a transfusion of blood plasma from […]

The post WHO recommends against the use of convalescent plasma to treat COVID-19. appeared first on Links Medicus.

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology  

The post Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. appeared first on Links Medicus.