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Observational study in adolescents showed the Pfizer-BioNTech vaccine had an overall effectiveness of 94% against hospitalization and 98% against critical Covid-19.

Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents – New England Journal of Medicine Editorial: Sparing of Severe Covid-19 in Vaccinated Adolescents – New England Journal of Medicine  

The post Observational study in adolescents showed the Pfizer-BioNTech vaccine had an overall effectiveness of 94% against hospitalization and 98% against critical Covid-19. appeared first on Links Medicus.

Study shows COVID-19 vaccines offer lasting protection against hospitalization and death.

Duration of Protection against Mild and Severe Disease by Covid-19 Vaccines – New England Journal of Medicine News Release: Study shows COVID-19 vaccines offer lasting protection – University of North Carolina at Chapel Hill  

The post Study shows COVID-19 vaccines offer lasting protection against hospitalization and death. appeared first on Links Medicus.

RCT: Endoscopic sinus surgery with medical therapy vs. medical therapy alone for chronic rhinosinusitis with nasal polyps.

Endoscopic sinus surgery with medical therapy versus medical therapy for chronic rhinosinusitis with nasal polyps: a multicentre, randomised, controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)   Commentary on Twitter NEW Research—Endoscopic sinus surgery + medical therapy > medical therapy alone in pts w/ chronic rhinosinusitis w/ nasal polyps […]

The post RCT: Endoscopic sinus surgery with medical therapy vs. medical therapy alone for chronic rhinosinusitis with nasal polyps. appeared first on Links Medicus.

RCT: Among patients younger than 21 years of age with provoked thromboembolism, anticoagulation for 6 weeks was non-inferior vs. 12 weeks on the risk of recurrence and bleeding events.

Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial – JAMA (free for a limited period) Editorial: Duration of Anticoagulant Treatment for Acute Provoked Venous Thromboembolism in Pediatric Patients – JAMA (free […]

The post RCT: Among patients younger than 21 years of age with provoked thromboembolism, anticoagulation for 6 weeks was non-inferior vs. 12 weeks on the risk of recurrence and bleeding events. appeared first on Links Medicus.

Discriminative accuracy of chronic obstructive pulmonary disease screening instruments in 3 low- and middle-income country settings.

Discriminative Accuracy of Chronic Obstructive Pulmonary Disease Screening Instruments in 3 Low- and Middle-Income Country Settings – JAMA (free for a limited period) Editorial: Screening for Chronic Obstructive Pulmonary Disease: Unmet Needs and Future Considerations News release: Simple screening for common lung disease could relieve millions globally – University College London   Commentary from the […]

The post Discriminative accuracy of chronic obstructive pulmonary disease screening instruments in 3 low- and middle-income country settings. appeared first on Links Medicus.

German Guideline: Oxygen therapy in the acute care of adult patients.

German S3 Guideline: Oxygen Therapy in the Acute Care of Adult Patients – Respiration  

The post German Guideline: Oxygen therapy in the acute care of adult patients. appeared first on Links Medicus.

Perspective | Covid-19: Is it safe to reduce the self-isolation period?

Covid-19: Is it safe to reduce the self-isolation period? – The BMJ  

The post Perspective | Covid-19: Is it safe to reduce the self-isolation period? appeared first on Links Medicus.

Podcast: Long COVID Pearls.

#315 Long COVID with Dr. Monica Verduzco-Gutierrez – The Curbsiders  

The post Podcast: Long COVID Pearls. appeared first on Links Medicus.

Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among t

The COVID-19 Treatment Guidelines Panel’s Statement on Potential Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications – NIH COVID-19 Treatment Guidelines Panel Commentaries: Pfizer antiviral pills may be risky with other medications – NBC News The New COVID-19 Pill, Paxlovid, Interacts with Many Medications: Cardiac Patients Take Note – The Skeptical Cardiologist See also: […]

The post Statement on potential drug-drug interactions between Ritonavir-boosted Nirmatrelvir (Paxlovid) and concomitant medications; antiarrhythmics, oral anticoagulants, immunosuppressants, anticonvulsants, antineoplastics, and neuropsychiatric drugs are among the drugs of concern. appeared first on Links Medicus.

The COVID-19 Treatment Guidelines Panel’s Statement on Anticoagulation in Hospitalized Patients With COVID-19 – in the absence of contraindications, use therapeutic-dose anticoagulation with low molecular weight heparin for hospitalized patients not in th