RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy.
Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial – JAMA Editorial: Defining Optimal Respiratory Support for Patients With COVID-19 – JAMA Commentary on Twitter RCT of patients with acute hypoxemic respiratory failure due to #COVID19 found an initial strategy […]
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A guide to immunotherapy for COVID-19.
A guide to immunotherapy for COVID-19 – Nature Medicine
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WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids.
WHO advisers weigh in on COVID-19 boosters, Pfizer vaccine in younger kids – CIDRAP See also: Interim recommendations for use of the Pfizer–BioNTech COVID-19 vaccine, BNT162b2, under Emergency Use Listing – World Health Organization
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Updated Guideline: Recommended drugs and biologics in adult patients with COVID-19.
Clinical Practice Guideline Summary: Recommended Drugs and Biologics in Adult Patients with COVID-19 – Covid-19 Advisory for Ontario Commentary on Twitter (thread – click for more) ?JUST RELEASED: New clinical guidelines for COVID now including #Paxlovid (nirmatrelvir/ritonavir). A ? on why Paxlovid is NOT first-line.https://t.co/h0puYpiFOK — Andrew Morris (@ASPphysician) January 22, 2022
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European CDC on Omicron: “among Omicron cases reported to TESSy, 1.14% were hospitalised, 0.16% required ICU admission/respiratory support, and 0.06% died”.
Weekly epidemiological update: Omicron variant of concern (VOC) – week 2 (data as of 20 January 2022) EU/EEA – European Centre for Disease Prevention and Control (ECDC)
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Case-control study: 3 doses of mRNA vaccines were associated with reduced infections with SARS-CoV-2 Omicron and Delta variants compared to no vaccination or 2 doses.
Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants – JAMA Editorial: Booster Vaccination to Prevent COVID-19 in the Era of Omicron: An Effective Part of a Layered Public Health Approach – JAMA Commentaries: New data show booster doses protect against Omicron – CIDRAP Boosters […]
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Review: Histiocytic disorders.
Histiocytic disorders – Nature Reviews Disease Primers (if the link is paywalled, try this one) Infographic: Histiocytic disorders (if the link is paywalled, try this one) Commentary on Twitter Haemophagocytic lympho #histiocytosis is a syndrome of extreme #immune activation; common manifestations include involvement of the central nervous system, hepatitis or acute liver failure.https://t.co/heXWqru8wW pic.twitter.com/1A0SFIhkwR […]
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Europe considers new COVID-19 strategy: Accepting the virus.
Europe considers new COVID-19 strategy: Accepting the virus – Associated Press
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Opinion: COVID-19 will continue but the end of the pandemic is near.
COVID-19 will continue but the end of the pandemic is near – The Lancet Commentary on Twitter .@IHME_UW's Chris Murray predicting the end of the pandemic is nigh"More than 50% of the world will have been infected with omicron …[by] the end of March, 2022""After the omicron wave, COVID-19 will return but the pandemic […]
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ATS Guideline: Outpatient respiratory management of infants, children, and adolescents with post-prematurity respiratory disease.
Outpatient Respiratory Management of Infants, Children, and Adolescents with Post-Prematurity Respiratory Disease: An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine News Release: Outpatient Management of Patients with Post-Prematurity Respiratory Disease: American Thoracic Society Publishes New Clinical Practice Guideline
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