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Beyond Omicron: what’s next for COVID’s viral evolution.

Beyond Omicron: what’s next for COVID’s viral evolution – Nature  

The post Beyond Omicron: what’s next for COVID’s viral evolution. appeared first on Links Medicus.

Video | COVID-19 Update: Omicron Variant.

COVID-19 Update: Omicron Variant – JAMA  

The post Video | COVID-19 Update: Omicron Variant. appeared first on Links Medicus.

Phase 2 RCT: Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule.

Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule, in healthy adults: interim results from two single-centre, double-blind, randomised, placebo-controlled phase 2 clinical trials – The Lancet Infectious Diseases Invited Commentary: Booster doses for inactivated COVID-19 vaccines: if, when, and for whom – The Lancet Infectious Diseases  

The post Phase 2 RCT: Immunogenicity and safety of a third dose of CoronaVac, and immune persistence of a two-dose schedule. appeared first on Links Medicus.

RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy.

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19: A Randomized Clinical Trial – JAMA Related: Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of […]

The post RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive mechanical ventilation and decreased the time to clinical recovery compared to conventional oxygen therapy. appeared first on Links Medicus.

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants.

A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants – STAT Original Study: SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection – medRxiv   Commentary from the author on Twitter (thread – click for more) We have completed our […]

The post A first, small study suggests Omicron is a larger threat to Covid-19 immunity than other variants. appeared first on Links Medicus.

WHO recommends against the use of convalescent plasma to treat COVID-19.

News Release: WHO recommends against the use of convalescent plasma to treat COVID-19 – World Health Organization See Guidance: WHO’s living guidelines on COVID-19 therapeutics Infographic: A living WHO guideline on drugs for covid-19 – The BMJ   Commentary on Twitter (thread – click for more) Convalescent plasma is a transfusion of blood plasma from […]

The post WHO recommends against the use of convalescent plasma to treat COVID-19. appeared first on Links Medicus.

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology  

The post Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. appeared first on Links Medicus.

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce.

Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce – Medical Journal of Australia  

The post Care of older people and people requiring palliative care with COVID-19: guidance from the Australian National COVID-19 Clinical Evidence Taskforce. appeared first on Links Medicus.

The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surge

The Risk of Postoperative Complications following Major Elective Surgery in Active or Resolved COVID-19 in the United States – Annals of Surgery Related: Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery Study from 116 countries suggests surgery should be delayed for at least seven weeks following a COVID-19 diagnosis to reduce mortality risk ASA Guidance: Preoperative […]

The post The risk of postoperative complications following major elective surgery in active or resolved COVID-19 in the United States – Major, elective surgery 0–4 weeks after Covid-19 is associated with greatly increased risk of postoperative complications; surgery performed 4–8 weeks after infection is still associated with an increased risk of pneumonia. appeared first on Links Medicus.

Clinical Review: Management of pneumonia in critically ill patients.

Management of pneumonia in critically ill patients – The BMJ  

The post Clinical Review: Management of pneumonia in critically ill patients. appeared first on Links Medicus.

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