With more data on its COVID-19 vaccine, Russian institute offers new evidence of success
With more data on its COVID-19 vaccine, Russian institute offers new evidence of success – Science News release: SECOND interim analysis of clinical trial data showed a 91.4% efficacy for the Sputnik V vaccine on day 28 after the first dose; vaccine efficacy is over 95% 42 days after the first dose – Sputnik V […]
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Cluster-randomized trial: Postexposure hydroxychloroquine does not prevent Covid-19 in healthy persons exposed to a PCR-positive case patient
A Cluster-Randomized Trial of Hydroxychloroquine for Prevention of Covid-19 – New England Journal of Medicine Commentary on Twitter Another RCT in @NEJM of outpatient treatment with Hydroxychloroquine in high risk folks to prevent COVID transmission No benefit But about 10X rate of adverse events in HCQ group Happy to keep studying HCQ But it […]
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Randomized trial: Convalescent Plasma does not improve clinical status or overall mortality in severe Covid-19 pneumonia
A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia – New England Journal of Medicine Commentary: New trial of convalescent plasma for covid-19 falls flat, another setback for hyped treatment – Brief19 Commentary on Twitter A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia @NEJM A well conducted RCT shows no significant […]
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Data show hospitalized Covid-19 patients are surviving at higher rates, but surge in cases could roll back gains
Data show hospitalized Covid-19 patients are surviving at higher rates, but surge in cases could roll back gains – STAT
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Emergency COVID-vaccine approvals pose a dilemma for scientists. It could complicate efforts to study long-term outcomes, such as safety, how long protection lasts and whether the jab prevents infection or just the disease
Why emergency COVID-vaccine approvals pose a dilemma for scientists – Nature
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Why does the AstraZeneca-Oxford COVID-19 vaccine’s efficacy vary so much? Here’s what we know
Why Does the AstraZeneca COVID-19 Vaccine’s Efficacy Vary So Much? Here’s What We Know – TIME Related: Why Oxford’s positive COVID vaccine results are puzzling scientists – Nature
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Why the AstraZeneca-Oxford Covid-19 vaccine is different. It does not require extremely cold temperatures for storage, and the price will be “a fraction” of the expense of the other vaccine candidates
Why the AstraZeneca-Oxford Covid-19 vaccine is different – Vox
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Diagnosis, management, and pathophysiology of arterial and venous thrombosis in COVID-19
Diagnosis, Management, and Pathophysiology of Arterial and Venous Thrombosis in COVID-19 – JAMA Commentary on Twitter Arterial and venous thrombosis are common in #COVID19, especially in critically ill patients. Thromboprophylaxis should be considered for all hospitalized patients with COVID-19 in the absence of contraindications https://t.co/sjqL7MqGLX — JAMA (@JAMA_current) November 23, 2020
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Meta-analysis: SARSCoV2 most contagious within the first 5 days of symptom onset
SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis – The Lancet Microbe Commentaries: COVID-19 most contagious in first 5 days of illness, study finds – CIDRAP AND Infectiousness peaks early in COVID-19 patients, emphasising the need to rapidly isolate cases – The Lancet AND Covid-19 […]
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Covid-19: Oxford University vaccine shows 70% protection
Covid-19: Oxford University vaccine shows 70% protection – BBC News release: Oxford University breakthrough on global COVID-19 vaccine Commentary on Twitter Today marks an important milestone in the fight against #COVID19. Interim data show the #OxfordVaccine is 70.4% effective, & tests on two dose regimens show that it could be 90%, moving us one […]
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