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Variant-proof vaccines — invest now for the next pandemic

Variant-proof vaccines — invest now for the next pandemic – Nature  

The post Variant-proof vaccines — invest now for the next pandemic appeared first on Links Medicus.

Thrombosis and COVID-19: Controversies and (Tentative) Conclusions

Thrombosis and COVID-19: Controversies and (Tentative) Conclusions – Clinical Infectious Diseases   Commentary on Twitter Excellent review of thrombosis and anticoagulation in #COVID19 by @connors_md and @RMKGandhi Paradoxically, anticoagulation may be most beneficial in moderately ill patients with #COVID19, as the bleeding risk may be excessive in the critically ill https://t.co/75TiNs0iej pic.twitter.com/v0avzhFl3f — John Ross […]

The post Thrombosis and COVID-19: Controversies and (Tentative) Conclusions appeared first on Links Medicus.

RCT: Posaconazole noninferior to voriconazole for primary treatment of invasive aspergillosis

Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)      

The post RCT: Posaconazole noninferior to voriconazole for primary treatment of invasive aspergillosis appeared first on Links Medicus.

Review: “Silent” Presentation of Hypoxemia and Cardiorespiratory Compensation in COVID-19

“Silent” Presentation of Hypoxemia and Cardiorespiratory Compensation in COVID-19 – Anesthesia  

The post Review: “Silent” Presentation of Hypoxemia and Cardiorespiratory Compensation in COVID-19 appeared first on Links Medicus.

Cohort study: ECMO in patients with severe respiratory failure from COVID-19

Extracorporeal membrane oxygenation in patients with severe respiratory failure from COVID-19 – Intensive Care Medicine Related: ECMO for COVID-19 patients in Europe and Israel – Intensive Care Medicine   Commentaries on Twitter #ECMO in #COVID19, multicenter US based study on 5122 critical adults➡️#ECLS in 3.7%, 66.8% of whom survived to hospital discharge or 60 days➡️considerably […]

The post Cohort study: ECMO in patients with severe respiratory failure from COVID-19 appeared first on Links Medicus.

What’s the risk of dying from a fast-spreading COVID-19 variant?

What’s the risk of dying from a fast-spreading COVID-19 variant? – Nature Original study: Increased hazard of death in community-tested cases of SARS-CoV-2 Variant of Concern 202012/01 – medRxiv  

The post What’s the risk of dying from a fast-spreading COVID-19 variant? appeared first on Links Medicus.

The good and the (potentially) bad: What scientists know about variants and Covid-19 vaccines

The good and the (potentially) bad: What scientists know about variants and Covid-19 vaccines – STAT See also: What Will it Take to Make Covid-19 Vaccines Variant-Proof? – Wired AND What’s Going On With All These Coronavirus Variants? An Illustrated Guide – NPR AND Video: Coronavirus Variants – What They Mean – JAMA  

The post The good and the (potentially) bad: What scientists know about variants and Covid-19 vaccines appeared first on Links Medicus.

[Press release – not published yet] Covid-19: Oxford vaccine offers less protection against South Africa variant

Oxford Covid-19 vaccine trial results – University of the Witwatersrand Commentaries: Covid: Oxford jab offers less S Africa variant protection – BBC AND Expert reaction to news reports that the Oxford/AZ vaccine gives limited protection against mild disease caused by the South African variant of SARS-CoV-2 – Science Media Centre AND Oxford/AstraZeneca COVID shot less […]

The post [Press release – not published yet] Covid-19: Oxford vaccine offers less protection against South Africa variant appeared first on Links Medicus.

[Press release – not published yet] Sinovac Announces Phase III Results of Its COVID-19 Vaccine

Sinovac Announces Phase III Results of Its COVID-19 Vaccine Commentaries: Expert reaction to announcement of results of phase III of Sinovac vaccine in China – Science Media Centre AND Sinovac says COVID-19 vaccine effective in preventing hospitalization, death – Reuters   Commentary on Twitter (thread – click for more) Sinovac's CoronaVac's phase 3 trial results: […]

The post [Press release – not published yet] Sinovac Announces Phase III Results of Its COVID-19 Vaccine appeared first on Links Medicus.

Case report: SARS-CoV-2 evolution in immunocompromised patient treated with convalescent plasma

SARS-CoV-2 evolution during treatment of chronic infection – Nature   Commentary on Twitter Just published @nature: The evolution of #SARSCoV2 in an immunocompromised patient, over > 100 days, that markedly accelerated once treated w/ convalescent plasma, with mutations that altered the response to neutralizing antibodies, by @GuptaR_lab https://t.co/SI4QL6BRXe pic.twitter.com/wqI1C2EYjQ — Eric Topol (@EricTopol) February 5, […]

The post Case report: SARS-CoV-2 evolution in immunocompromised patient treated with convalescent plasma appeared first on Links Medicus.

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