Covid-19: In vitro studies show Pfizer-BioNTech and Moderna vaccines produce fewer antibodies against South African variant
Study 1: Neutralizing Activity of BNT162b2-Elicited Serum — Preliminary Report – New England Journal of Medicine Study 2: Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine — Preliminary Report – New England Journal of Medicine Commentaries: Expert reaction to two NEJM Correspondence articles on in vitro studies of the Pfizer-BioNTech and Moderna vaccines and different variants/mutations […]
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M-A: The effect of convalescent plasma therapy on COVID-19 patient mortality
The Effect of Convalescent Plasma Therapy on COVID-19 Patient Mortality: Systematic Review and Meta-analysis – Mayo Clinic Proceedings Related study (not published yet) with conflicting results: RECOVERY trial: No Benefit from convalescent plasma in hospitalized patients with Covid-19 (news release and commentary)
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Video: Emergency intubation in Covid-19
Emergency Intubation in Covid-19 – New England Journal of Medicine
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RCT: Vitamin D3 does not improve outcomes in hospitalized patients with moderate to severe COVID-19
Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial – JAMA Editorial: Vitamin D3 to Treat COVID-19: Different Disease, Same Answer In this RCT a single high dose of #vitaminD3 (100K IU) raised mean serum 25OH D levels but had […]
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RCT: Avacopan for the treatment of ANCA-associated vasculitis
Avacopan for the Treatment of ANCA-Associated Vasculitis – New England Journal of Medicine (link to abstract – $ for full-text)
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Why more contagious variants are emerging now, more than a year into the COVID-19 pandemic
Why more contagious variants are emerging now, more than a year into the COVID-19 pandemic – The Conversation
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Podcast: Sarcoidosis
#256 Sarcoidosis – The Curbsiders Internal Medicine Podcast
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Effectiveness of telerehabilitation in physical therapy: A rapid overview
Effectiveness of telerehabilitation in physical therapy: A rapid overview – Physical Therapy
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Opinion: RECOVERY confirms benefit of tocilizumab combined with dexamethasone
PulmCrit – RECOVERY confirms benefit of toci combined with dexamethasone Original study: RCT: Tocilizumab reduces deaths in patients hospitalized with COVID-19 (study and commentaries)
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Potential health and economic impacts of dexamethasone treatment for patients with COVID-19
Potential health and economic impacts of dexamethasone treatment for patients with COVID-19 – Nature Communications Commentary on Twitter RCTs Save Live$DEXA saves live$Potential health&economic impacts of dexamethasone treatment for #COVID19 patientsThe study estimate that between July & Dec 2020, for ??, ~12,000 lives could be saved & ~650,000 lives saved globally over the same […]
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