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RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19.

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial – The Lancet Respiratory Medicine   Commentary on Twitter ?Just OutACTT-4 Trial?First Double Placebo-Controlled Double-Blind Randomized-Stratified Head-to-Head#DEXAMETHASONE vs #BARICITINIB for hospitalized pts w/#COVID19 Low/High-Flow/NIVRelevant?Patient Care/Public Health/GuidelinesOur results?https://t.co/4Tmue7HK7V ?1/4 pic.twitter.com/aF1Y7BAdu3 — Andre Kalil, MD MPH (@DrAndreKalil) May 24, 2022  

The post RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19. appeared first on Links Medicus.

Modeling Study: 20% of multi-drug resistant tuberculosis cases in children could be averted by household testing and treatment.

News Release: 20% of multi-drug resistant tuberculosis cases in children could be averted by household testing and treatment – London School of Hygiene & Tropical Medicine Original Study: The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study – The Lancet […]

The post Modeling Study: 20% of multi-drug resistant tuberculosis cases in children could be averted by household testing and treatment. appeared first on Links Medicus.

Systematic Review: Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin.

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin – Cochrane Library Summary: Xpert MTB/XDR, a rapid test for resistance to tuberculosis drugs – Cochrane Library  

The post Systematic Review: Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin. appeared first on Links Medicus.

Cohort Study: Risk of venous thromboembolism in men with prostate cancer compared with men in the general population.

Risk of venous thromboembolism in men with prostate cancer compared with men in the general population: a nationwide population-based cohort study in Sweden – BMJ Open News Release: Men with prostate cancer have a higher risk of serious blood clots – BMJ   Commentary on Twitter Men with prostate cancer have a 50% higher risk […]

The post Cohort Study: Risk of venous thromboembolism in men with prostate cancer compared with men in the general population. appeared first on Links Medicus.

Cohort Study: Analysis of neuropsychiatric diagnoses after montelukast initiation.

Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation – JAMA Network Open Related: FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); advises restricting use for allergic rhinitis – U.S. Food & Drug Administration Adverse drug reactions of montelukast in children and adults – Pharmacology Research & Perspectives […]

The post Cohort Study: Analysis of neuropsychiatric diagnoses after montelukast initiation. appeared first on Links Medicus.

Cohort Study: Pneumococcal urinary antigen testing for antimicrobial guidance in community-acquired pneumonia.

Pneumococcal urinary antigen testing for antimicrobial guidance in community-acquired pneumonia: a register-based cohort study – Journal of Infection   Commentary on Twitter ??Large register-based cohort studyTo evaluate the effect of pneumococcal urinary antigen test usage on broad-spectrum antibiotic treatment in CAPPerforming urinary antigen test has little effect on antibiotic therapy in pneumonia #IDTwitterhttps://t.co/Cxg9FDEUqk — Antibiotic […]

The post Cohort Study: Pneumococcal urinary antigen testing for antimicrobial guidance in community-acquired pneumonia. appeared first on Links Medicus.

RCT: High-flow nasal oxygen is not beneficial for patients with COVID-19 pneumonia and mild hypoxemia.

High-flow nasal oxygen versus conventional oxygen therapy in patients with COVID-19 pneumonia and mild hypoxaemia: a randomised controlled trial – Thorax  

The post RCT: High-flow nasal oxygen is not beneficial for patients with COVID-19 pneumonia and mild hypoxemia. appeared first on Links Medicus.

NICE rapid guideline update on the management of Covid-19.

COVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence  

The post NICE rapid guideline update on the management of Covid-19. appeared first on Links Medicus.

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update.

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology   Commentary on Twitter Just published ?? @ICHEJournal @SHEA_Epi @IDSAInfo @APICStrategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update #IDTwitter https://t.co/fipGfkyHi6 pic.twitter.com/c88X5GL0d6 — Antibiotic Steward Bassam […]

The post Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update. appeared first on Links Medicus.

Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality.

Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality – Intensive Care Medicine   Commentary on Twitter CMV reactivation in #COVID19 critically ill pts:?frequent! >20% in this study?risk depends on severity of illness/occurrence of secondary bacterial infections in #ICU? prolonged hospital stay & higher mortality but independent association lacking.? https://t.co/N8JVD1GyPQ […]

The post Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality. appeared first on Links Medicus.

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