RCT: Effect of varenicline added to counseling on smoking cessation among African American daily smokers.
Effect of Varenicline Added to Counseling on Smoking Cessation Among African American Daily Smokers: The Kick It at Swope IV Randomized Clinical Trial – JAMA Network Open Editorial: Helping African American Individuals Quit Smoking: Finally, Some Progress – JAMA News Release: Varenicline Increases Smoking Cessation Rates for African American Smokers – University of Kansas Cancer […]
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Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations.
Pfizer’s Paxlovid study fails to answer key questions over benefit for broader populations – STAT
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Cohort Study | Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration.
Intermediate-risk pulmonary embolism: echocardiography predictors of clinical deterioration – Critical Care
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M-A: Treatment outcomes among pregnant patients with multidrug-resistant tuberculosis.
Treatment Outcomes Among Pregnant Patients With Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis – JAMA Network Open Commentary on Twitter This meta-analysis of pregnant patients treated for multi-drug-resistant tuberculosis (MDR-TB) found 73% treatment success and 73% favorable pregnancy outcomes, with adverse events (incl liver/kidney impairment, hearing loss) in more than half of patients. https://t.co/Mx5RLiwhU9 […]
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Study among patients with sleep apnea showed multimorbidity was present in two-thirds of individuals at the time of diagnosis.
Multimorbidity and overall comorbidity of sleep apnoea: a Finnish nationwide study – ERJ Open Research Commentary: Study Highlights Prevalence of OSA and Overall Burden of Comorbidities – AJMC Commentary on Twitter Two-thirds of individuals with sleep apnoea are multimorbid at diagnosis and one-third are heavily multimorbid. Dorsopathies, musculoskeletal diseases, hypertension and metabolic diseases are […]
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[Preprint] RCT: Ivermectin does not benefit patients with mild-to-moderate COVID-19 in the outpatient setting.
Ivermectin for Treatment of Mild-to-Moderate COVID-19 in the Outpatient Setting: A Decentralized, Placebo-controlled, Randomized, Platform Clinical Trial – medRxiv Commentary: Study finds no benefit to taking ivermectin for COVID-19 symptoms – Duke University
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Systematic Review: Janus kinase inhibitors for the treatment of COVID‐19.
Janus kinase inhibitors for the treatment of COVID‐19 – Cochrane Library Summary: Are systemic Janus kinase inhibitors an effective treatment for people with COVID-19? – Cochrane Library
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RCT: Intramuscular tixagevimab–cilgavimab may benefit non-hospitalized unvaccinated adults with Covid-19.
Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial – The Lancet Respiratory Medicine Commentaries: Safety and efficacy of tixagevimab–cilgavimab in preventing severe COVID – News Medical Expert reaction to results of the TACKLE Phase 3 trial of Evusheld (tixagevimab and cilgavimab) […]
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M-A: Respiratory viral co-infections in patients with COVID-19 and associated outcomes.
Respiratory viral co-infections in patients with COVID-19 and associated outcomes: A systematic review and meta-analysis – Reviews in Medical Virology
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NIH Updated Guideline: Oxygenation and ventilation for adults with Covid-19.
Oxygenation and Ventilation for Adults – National Institutes of Health
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