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Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening.

Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening – Intensive Care Medicine   Commentary on Twitter RV failure in moderate-to-severe #COVID19 #ARDS➡️strong predictor of mortality➡️significant worsening of PaO2/FiO2, PaCO2 & ventilatory ratio (⬆️ pulm vasoconstriction) & ⬆️ driving P could contribute#POCUS mandatory especially […]

The post Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening. appeared first on Links Medicus.

Test-negative, case–control study: effectiveness of homologous and heterologous Covid-19 boosters against Omicron.

Effectiveness of Homologous and Heterologous Covid-19 Boosters against Omicron – New England Journal of Medicine  

The post Test-negative, case–control study: effectiveness of homologous and heterologous Covid-19 boosters against Omicron. appeared first on Links Medicus.

Cohort Study: Protection and waning of natural and hybrid immunity to SARS-CoV-2.

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine Editorial: Audio Interview: Waning Immunity against Covid-19   Commentary on Twitter Protection against SARS-CoV-2 waned over time in both vaccinated and previously infected persons; an additional vaccine dose restored protection, find investigators from Israel. https://t.co/617uBmWu8l pic.twitter.com/yiDnBbCuQ5 — NEJM (@NEJM) […]

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Cohort Study: Trajectory of long covid symptoms after covid-19 vaccination.

Trajectory of long covid symptoms after covid-19 vaccination: community based cohort study – The BMJ Editorial: Are vaccines a potential treatment for long covid? – The BMJ News Release: Vaccination after SARS-CoV-2 infection linked to a decrease in long covid symptoms – BMJ Newsroom   Commentary on Twitter LONG COVID: Number of well controlled studies […]

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Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows.

Commentary: Long COVID risk falls only slightly after vaccination, huge study shows – Nature Original Study: Long COVID after breakthrough SARS-CoV-2 infection – Nature Medicine   Commentary from the author on Twitter (thread – click for more) The latest from our team in @NatureMedicine Does vaccination protect from #LongCovid? Vaccines modestly reduce but do not […]

The post Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows. appeared first on Links Medicus.

RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19.

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial – The Lancet Respiratory Medicine   Commentary on Twitter ?Just OutACTT-4 Trial?First Double Placebo-Controlled Double-Blind Randomized-Stratified Head-to-Head#DEXAMETHASONE vs #BARICITINIB for hospitalized pts w/#COVID19 Low/High-Flow/NIVRelevant?Patient Care/Public Health/GuidelinesOur results?https://t.co/4Tmue7HK7V ?1/4 pic.twitter.com/aF1Y7BAdu3 — Andre Kalil, MD MPH (@DrAndreKalil) May 24, 2022  

The post RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19. appeared first on Links Medicus.

Modeling Study: 20% of multi-drug resistant tuberculosis cases in children could be averted by household testing and treatment.

News Release: 20% of multi-drug resistant tuberculosis cases in children could be averted by household testing and treatment – London School of Hygiene & Tropical Medicine Original Study: The global impact of household contact management for children on multidrug-resistant and rifampicin-resistant tuberculosis cases, deaths, and health-system costs in 2019: a modelling study – The Lancet […]

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Systematic Review: Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin.

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin – Cochrane Library Summary: Xpert MTB/XDR, a rapid test for resistance to tuberculosis drugs – Cochrane Library  

The post Systematic Review: Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and amikacin. appeared first on Links Medicus.

Cohort Study: Risk of venous thromboembolism in men with prostate cancer compared with men in the general population.

Risk of venous thromboembolism in men with prostate cancer compared with men in the general population: a nationwide population-based cohort study in Sweden – BMJ Open News Release: Men with prostate cancer have a higher risk of serious blood clots – BMJ   Commentary on Twitter Men with prostate cancer have a 50% higher risk […]

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Cohort Study: Analysis of neuropsychiatric diagnoses after montelukast initiation.

Analysis of Neuropsychiatric Diagnoses After Montelukast Initiation – JAMA Network Open Related: FDA requires Boxed Warning about serious mental health side effects for asthma and allergy drug montelukast (Singulair); advises restricting use for allergic rhinitis – U.S. Food & Drug Administration Adverse drug reactions of montelukast in children and adults – Pharmacology Research & Perspectives […]

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