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Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination – Nature Medicine Commentary: A ‘mix and match’ approach to SARS-CoV-2 vaccination – Nature Medicine Related: WHO warns against mixing and matching COVID vaccines. Germany issues world’s strongest recommendation for mixing Covid-19 vaccines. Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 […]

The post Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination. appeared first on Links Medicus.

[Preprint] Covid-19: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity.

News release: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity – Newcastle University Original Study (preprint): Sustained T cell immunity, protection and boosting using extended dosing intervals of BNT162b2 mRNA vaccine Commentaries: Commentary: Covid-19: Longer interval between Pfizer doses results in higher antibody levels, research finds – BMJ Expert reaction to preprint from PITCH […]

The post [Preprint] Covid-19: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity. appeared first on Links Medicus.

Review: Long covid—mechanisms, risk factors, and management.

Long covid—mechanisms, risk factors, and management – The BMJ   Commentary on Twitter Great review in @bmj_latest of what we know – and all that we don't – about Long Covid. Including this graphic of different ways it can manifest. article here https://t.co/zsqNVNVEo8 https://t.co/V4C5aJbpg0 pic.twitter.com/5XU1W557wQ — Prof. Christina Pagel (@chrischirp) July 26, 2021  

The post Review: Long covid—mechanisms, risk factors, and management. appeared first on Links Medicus.

Case report: Kawasaki-like multisystem inflammatory syndrome associated with SARS-CoV-2 infection in an adult.

Kawasaki-like multisystem inflammatory syndrome associated with SARS-CoV-2 infection in an adult – BMJ Case Reports Related: Case report: Multisystem inflammatory syndrome in an adult after SARS-CoV-2 infection. Characteristics associated with Multisystem Inflammatory Syndrome among adults with SARS-CoV-2 infection Case series of multisystem inflammatory syndrome in adults associated with SARS-CoV-2 infection Case Reports: 2 Adults with […]

The post Case report: Kawasaki-like multisystem inflammatory syndrome associated with SARS-CoV-2 infection in an adult. appeared first on Links Medicus.

Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients.

Antibody Response After a Third Dose of the mRNA-1273 SARS-CoV-2 Vaccine in Kidney Transplant Recipients With Minimal Serologic Response to 2 Doses – JAMA Commentary: Case Mounts for COVID Vaccine Boosters in Kidney Transplant Recipients – MedPage Today (free registration required) Related: Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in […]

The post Study: Among kidney transplant recipients who did not respond after 2 doses, a third dose of an mRNA-1273 vaccine induced a serologic response in 49% of patients. appeared first on Links Medicus.

Study: Lateral flow antigen testing can rapidly and accurately detect early COVID-19 among patients presenting with flu-like illness and can be a plausible alternative to RT-PCR.

Comparing the diagnostic accuracy of point-of-care lateral flow antigen testing for SARS-CoV-2 with RT-PCR in primary care (REAP-2) – EClinicalMedicine News release: Lateral flow tests are 95% effective at detecting Covid-19 when used at the onset of symptoms – University of Oxford Related: Interactive Infographic | Interpreting a lateral flow SARS-CoV-2 antigen test – “This […]

The post Study: Lateral flow antigen testing can rapidly and accurately detect early COVID-19 among patients presenting with flu-like illness and can be a plausible alternative to RT-PCR. appeared first on Links Medicus.

M-A: Psychiatric patients at increased risk of COVID-19 hospitalization and mortality.

News release: Psychiatric patients at increased risk of COVID-19 hospitalization and mortality – European College of Neuropsychopharmacology Original article: Mental disorders and risk of COVID-19-related mortality, hospitalisation, and intensive care unit admission: a systematic review and meta-analysis – The Lancet Psychiatry  

The post M-A: Psychiatric patients at increased risk of COVID-19 hospitalization and mortality. appeared first on Links Medicus.

Large cohort study finds one in two hospitalized COVID-19 patients develop a complication.

Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study – The Lancet Commentaries: Landmark study finds one in two hospitalised COVID-19 patients develop a complication – National Institute for Health Research In-hospital complications associated with COVID-19 – The Lancet CV Complications Common in Hospitalized […]

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[Preprint] RCT: In patients with COVID-19 and severe hypoxia, dexamethasone 12 mg did NOT result in statistically significant improved outcomes compared to dexamethasone 6 mg – “Mortality at 28 days was 27.1% and 32.3% in patients assigned to 12 mg and 6

Position paper: Advancing precision medicine for acute respiratory distress syndrome.

Advancing precision medicine for acute respiratory distress syndrome – The Lancet Respiratory Medicine Related: Review: Personalized mechanical ventilation in acute respiratory distress syndrome. Seminar | Acute respiratory distress syndrome. M-A of randomized trials: In patients with acute respiratory distress syndrome, there was no difference in mortality between higher vs. lower positive end-expiratory pressure strategies. M-A: […]

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