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WHO reports progress in the fight against tobacco epidemic – Highlights threats posed by new nicotine and tobacco products.

News release: WHO reports progress in the fight against tobacco epidemic – World Health Organization Report: WHO report on the global tobacco epidemic 2021: New and Emerging Products – World Health Organization Commentary: While Global Tobacco Control Measures Improve, Electronic Cigarettes Evade Regulation in Many Countries – Health Policy Watch   Commentary on Twitter (thread […]

The post WHO reports progress in the fight against tobacco epidemic – Highlights threats posed by new nicotine and tobacco products. appeared first on Links Medicus.

Household transmission of SARS-CoV-2 from children and adolescents.

Household Transmission of SARS-CoV-2 from Children and Adolescents – New England Journal of Medicine Related: Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in […]

The post Household transmission of SARS-CoV-2 from children and adolescents. appeared first on Links Medicus.

COVID-19 and mucormycosis superinfection: the perfect storm.

COVID-19 and mucormycosis superinfection: the perfect storm – Infection Related: ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries. The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested […]

The post COVID-19 and mucormycosis superinfection: the perfect storm. appeared first on Links Medicus.

Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2

Very rare thrombosis with thrombocytopenia after second AZD1222 dose: a global safety database analysis – The Lancet Related: WHO Guidance for clinical case management of thrombosis with thrombocytopenia syndrome (TTS) following vaccination to prevent coronavirus disease (COVID-19). AHA/ASA Guidance: Diagnosis and Management of Cerebral Venous Sinus Thrombosis with Vaccine-Induced Thrombotic Thrombocytopenia – “No heparin products […]

The post Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a global safety database analysis – the estimated rate of TTS after the first dose was 8.1 per million vaccinees; after the second dose, the estimated rate was 2.3 per million vaccinees. appeared first on Links Medicus.

CoronaVac vaccine: its results are patchy, but the world can’t ignore its usefulness.

CoronaVac vaccine: its results are patchy, but the world can’t ignore its usefulness – The Conversation Related: RCT: CoronaVac showed efficacy of 83.5% for preventing symptomatic SARS-CoV-2 infection. Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death. Phase 1/2 RCT: CoronaVac […]

The post CoronaVac vaccine: its results are patchy, but the world can’t ignore its usefulness. appeared first on Links Medicus.

[Preprint] Test-negative case-control study: Effectiveness of CoronaVac vaccine in order people during SARS-CoV-2 Gamma variant transmission in Brazil – Adjusted vaccine effectiveness was 41.6% for symptomatic Covid-19, 59.0% against hospitalizations and

Effectiveness of the CoronaVac vaccine in the elderly population during a Gamma variant-associated epidemic of COVID-19 in Brazil: A test-negative case-control study – medRxiv   Commentary on Twitter (thread – click for more) Two new results on vaccine effectiveness of #CoronaVac and #AstraZeneca in #Brazil w/ @otavio_ranzani @juliocroda @datcummings Albert Ko, Jason Andrews and othershttps://t.co/grIg1ydMK6https://t.co/fGmDsi7NdL […]

The post [Preprint] Test-negative case-control study: Effectiveness of CoronaVac vaccine in order people during SARS-CoV-2 Gamma variant transmission in Brazil – Adjusted vaccine effectiveness was 41.6% for symptomatic Covid-19, 59.0% against hospitalizations and 71.4% against deaths. appeared first on Links Medicus.

[Preprint] Test-negative case-control study: Effectiveness of Oxford-AstraZeneca vaccine in order people during SARS-CoV-2 Gamma variant transmission in Brazil – Adjusted effectiveness was 77.9% for symptomatic Covid-19, 87.6% against hospitalization, and

Effectiveness of the ChAdOx1 vaccine in the elderly during SARS-CoV-2 Gamma variant transmission in Brazil – medRxiv   Commentary on Twitter (thread – click for more) Two new results on vaccine effectiveness of #CoronaVac and #AstraZeneca in #Brazil w/ @otavio_ranzani @juliocroda @datcummings Albert Ko, Jason Andrews and othershttps://t.co/grIg1ydMK6https://t.co/fGmDsi7NdL 1/8 — Matt Hitchings (@MHitchingsEpi) July 23, […]

The post [Preprint] Test-negative case-control study: Effectiveness of Oxford-AstraZeneca vaccine in order people during SARS-CoV-2 Gamma variant transmission in Brazil – Adjusted effectiveness was 77.9% for symptomatic Covid-19, 87.6% against hospitalization, and 93.6% against death. appeared first on Links Medicus.

Safety evaluation of the second dose of mRNA COVID-19 vaccines in patients with immediate reactions to the first dose.

Safety Evaluation of the Second Dose of Messenger RNA COVID-19 Vaccines in Patients With Immediate Reactions to the First Dose – JAMA Internal Medicine Commentaries: Second COVID-19 mRNA vaccine dose found safe following allergic reactions to first dose – Massachusetts General Hospital No anaphylaxis after second dose of mRNA COVID vaccine, study finds – CIDRAP […]

The post Safety evaluation of the second dose of mRNA COVID-19 vaccines in patients with immediate reactions to the first dose. appeared first on Links Medicus.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Immunogenicity and reactogenicity of heterologous ChAdOx1 nCoV-19/mRNA vaccination – Nature Medicine Commentary: A ‘mix and match’ approach to SARS-CoV-2 vaccination – Nature Medicine Related: WHO warns against mixing and matching COVID vaccines. Germany issues world’s strongest recommendation for mixing Covid-19 vaccines. Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 […]

The post Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination. appeared first on Links Medicus.

[Preprint] Covid-19: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity.

News release: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity – Newcastle University Original Study (preprint): Sustained T cell immunity, protection and boosting using extended dosing intervals of BNT162b2 mRNA vaccine Commentaries: Commentary: Covid-19: Longer interval between Pfizer doses results in higher antibody levels, research finds – BMJ Expert reaction to preprint from PITCH […]

The post [Preprint] Covid-19: Longer interval between Covid-19 Pfizer vaccine doses boosts immunity. appeared first on Links Medicus.