Clinical Picture: Mucormycosis after COVID-19 in a patient with diabetes.
Mucormycosis after COVID-19 in a patient with diabetes – The Lancet Related: COVID-19 and mucormycosis superinfection: the perfect storm. ECMM/ISHAM recommendations for clinical management of COVID -19 associated mucormycosis in low- and middle-income countries. The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring […]
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Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients.
Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients – Critical Care
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Systematic Review: “Remdesivir probably has little or no effect on all‐cause mortality at up to 28 days in hospitalized adults with SARS‐CoV‐2 infection. We are uncertain about the effects of remdesivir on clinical improvement and worsening”.
Remdesivir for the treatment of COVID‐19 – Cochrane Library Summary: Remdesivir for the treatment of COVID-19 – Cochrane Library Commentary on Twitter (thread – click for more) JUST PUBLISHED – Is #remdesivir an effective treatment for #COVID19? https://t.co/ntgfDQjMqs This @CochraneHaem systematic review looked at this antiviral medicine to see if it's an effective treatment […]
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[Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP reduced the composite outcome of intubation or death within 30 days; high-flow nasal oxygenation was not associated with better outcomes.
An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 – medRxiv Commentary: Covid: Pressured oxygen reduces ventilator need – BBC Commentary on Twitter (thread – click for more) RECOVERY-RS results out, and confirm what most of us have been doing: CPAP reduces intubation/mortality by 28% compared with […]
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International, multicenter observational study: Outcomes with percutaneous dilatational tracheotomy in high-risk ICU patients.
Percutaneous dilatational tracheotomy in high-risk ICU patients – Annals of Intensive Care
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RCT: In noncritically ill patients hospitalized with Covid-19, therapeutic-dose anticoagulation with heparin increased the probability of survival to hospital discharge compared with usual-care thromboprophylaxis.
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 – New England Journal of Medicine Editorial: Surviving Covid-19 with Heparin? Commentaries: Full-dose blood thinners reduce the need for organ support in moderately ill COVID-19 patients, but not in critically ill patients – National Institutes of Health Therapeutic-Dose Heparin in COVID-19: Who Benefits, Who Doesn’t […]
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Review: Tuberous sclerosis complex for the pulmonologist.
Tuberous sclerosis complex for the pulmonologist – European Respiratory Review
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Review: Lung transplantation for interstitial lung disease.
Lung transplantation for interstitial lung disease – European Respiratory Review
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RCT: Subcutaneous REGEN-COV antibody combination prevented symptomatic Covid-19 infection in previously uninfected household contacts of infected persons.
Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 – New England Journal of Medicine Related: RCT: Bamlanivimab plus Etesevimab reduce mortality and hospitalization in ambulatory patients with early Covid-19 (within 3 days of a positive test) who are at risk for clinical deterioration (i.e., older people, obese, diabetics, immunocompromised, with CV disease). [Preprint] RECOVERY trial finds […]
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SARS-CoV-2 Variants in Patients with Immunosuppression.
SARS-CoV-2 Variants in Patients with Immunosuppression – New England Journal of Medicine Commentary on Twitter In the pandemic, immunocompromised people (~3% of Americans) are not getting adequate recognition for the potential of in-host evolution of the virus (highlighted studies) and the need for far better approaches to protect them https://t.co/XDT1VxC9ZK @NEJM pic.twitter.com/ciw1WD9EzC — Eric […]
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