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RCT: Evaluation of Moderna mRNA vaccine in adolescents.

Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents – New England Journal of Medicine Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. RCT: Pfizer-BioNTech Covid-19 vaccine shows 100% efficacy in adolescents – mainly transient mild-to-moderate reactogenicity was frequently observed, such as injection-site […]

The post RCT: Evaluation of Moderna mRNA vaccine in adolescents. appeared first on Links Medicus.

2021 guidelines for management of venous thromboembolism in Latin America.

ASH, ABHH, ACHO, Grupo CAHT, Grupo  CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panameña de Hematología, SPH, and SVH 2021 guidelines for management of venous thromboembolism in Latin America – Blood Advances  

The post 2021 guidelines for management of venous thromboembolism in Latin America. appeared first on Links Medicus.

Video: Frequently Asked COVID-19 Vaccine Questions – August 2021 Update.

Frequently Asked COVID-19 Vaccine Questions – August 2021 Update – JAMA  

The post Video: Frequently Asked COVID-19 Vaccine Questions – August 2021 Update. appeared first on Links Medicus.

WHO’s Solidarity clinical trial enters a new phase with three new candidate drugs.

WHO’s Solidarity clinical trial enters a new phase with three new candidate drugs – World Health Organization Commentary: WHO-led Trial Will Test Malaria and Cancer Medicines Against COVID-19 – Health Policy Watch Related: A giant trial of COVID-19 treatments organized by the WHO is restarting. Here are the drugs it’s betting on. WHO Solidarity trial […]

The post WHO’s Solidarity clinical trial enters a new phase with three new candidate drugs. appeared first on Links Medicus.

Clinical features of vaccine-induced immune thrombocytopenia and thrombosis.

Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis – New England Journal of Medicine Commentary: Largest Study of VITT After COVID-19 Vaccination Digs Into Lab, Clinical Features – TCTMD Related: Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis. NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and […]

The post Clinical features of vaccine-induced immune thrombocytopenia and thrombosis. appeared first on Links Medicus.

RCT: Triaging acute pulmonary embolism for home treatment by Hestia vs. simplified PESI criteria – the tools were similarly effective, and more than a third of patients were treated at home with a low incidence of complications.

Triaging acute pulmonary embolism for home treatment by Hestia or simplified PESI criteria: the HOME-PE randomized trial – European Heart Journal   Commentary on Twitter Triaging acute pulmonary embolism for home treatment by Hestia or simplified PESI criteria: the HOME-PE randomized trial #EHJ #PE #PERThttps://t.co/gszusChSyU pic.twitter.com/NOyKYsVQHo — EHJ Editor-in-Chief (@ehj_ed) August 10, 2021  

The post RCT: Triaging acute pulmonary embolism for home treatment by Hestia vs. simplified PESI criteria – the tools were similarly effective, and more than a third of patients were treated at home with a low incidence of complications. appeared first on Links Medicus.

Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis.

Clinical Characteristics and Pharmacological Management of COVID-19 Vaccine–Induced Immune Thrombotic Thrombocytopenia With Cerebral Venous Sinus Thrombosis: A Review – JAMA Cardiology Related: NICE COVID-19 rapid guideline: vaccine-induced immune thrombocytopenia and thrombosis. Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know. Very rare cases of thrombosis with thrombocytopenia syndrome (TTS) after AstraZeneca vaccine: a […]

The post Review: Clinical characteristics and pharmacological management of COVID-19 vaccine–induced immune thrombotic thrombocytopenia with cerebral venous sinus thrombosis. appeared first on Links Medicus.

CDC Report: COVID-19 morbidity and mortality far exceed the potential risks of rare side effects caused by vaccines.

Use of COVID-19 Vaccines After Reports of Adverse Events Among Adult Recipients of Janssen (Johnson & Johnson) and mRNA COVID-19 Vaccines (Pfizer-BioNTech and Moderna): Update from the Advisory Committee on Immunization Practices — United States, July 2021 – CDC Morbidity and Mortality Weekly Report  

The post CDC Report: COVID-19 morbidity and mortality far exceed the potential risks of rare side effects caused by vaccines. appeared first on Links Medicus.

M-A: More than 50 long-term effects of COVID-19.

More than 50 long-term effects of COVID-19: a systematic review and meta-analysis – Scientific Reports Related: Illness duration and symptom profile in symptomatic school-aged children tested for SARS-CoV-2 – “Only 25 (1.8%) of 1379 children experienced symptoms for at least 56 days.” Cohort study: Risk factors for long covid in previously hospitalized children. Viewpoint: The […]

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M-A: Asymptomatic SARS-CoV-2 infection – “we estimate that the percentage of infections that never developed clinical symptoms, and thus were truly asymptomatic, was 35.1%”.

Asymptomatic SARS-CoV-2 infection: A systematic review and meta-analysis – Proceedings of the National Academy of Sciences   Commentary on Twitter The best comprehensive review of the asymptomatic status with Covid, >350 studies, just out @PNASNews https://t.co/xyfgyGXANLOverall: true, never had symptoms 35%; children 47%@Pratha_Sah @Alison_Galvani @MeaganCFitz @YaleSPH & colleagues(wonder what the rate is w/ Delta) pic.twitter.com/9W6wbvQno6 […]

The post M-A: Asymptomatic SARS-CoV-2 infection – “we estimate that the percentage of infections that never developed clinical symptoms, and thus were truly asymptomatic, was 35.1%”. appeared first on Links Medicus.