How will Delta evolve? Here’s what the theory tells us.
How will Delta evolve? Here’s what the theory tells us – The Conversation
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Opinion | The FDA really did have to take this long – “If vaccine approval feels maddeningly scrupulous, that’s because the alternative is worse”.
The FDA Really Did Have to Take This Long – The Atlantic
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Covid-19 booster vaccines: What we know and who’s doing what.
Covid-19 booster vaccines: What we know and who’s doing what – The BMJ
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[Preprint] RCT: Fluvoxamine reduced the risk for ER visits and hospitalization among patients with Covid-19.
RCT: Effect of Early Treatment with Fluvoxamine on Risk of Emergency Care and Hospitalization Among Patients with COVID-19 – Together Clinical Trials Related: Opinion | Could this be our first effective, inexpensive, widely available outpatient treatment for COVID-19? (It’s fluvoxamine). Preliminary study shows fluvoxamine may reduce clinical deterioration in outpatients with symptomatic COVID-19 Commentary […]
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Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.
Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort study – The Lancet Respiratory Medicine Invited Commentary: Heterologous ChAdOx1-nCoV19–BNT162b2 vaccination provides superior immunogenicity against COVID-19 Related: Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant. RCT: Safety and immunogenicity of heterologous […]
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Study Commentaries: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial.
Commentary 1: JC: Non-invasive ventilation for COVID 19 patients. The Recovery RS trial – St Emlyn’s Commentary 2: An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 – The Bottom Line Original study: [Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP […]
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Among patients receiving mRNA vaccines, clinically significant symptoms were more frequent following dose 2, following dose 1 in patients with previous SARS-CoV-2 infection, and in those who received the Moderna vaccine.
Association of Vaccine Type and Prior SARS-CoV-2 Infection With Symptoms and Antibody Measurements Following Vaccination Among Health Care Workers – JAMA Internal Medicine Commentary on Twitter New @JAMA_current paper says @moderna_Tx caused 2.3x the number of "significant" symptoms compared to @pfizer in a sample of 950 people. Moderna also produced more antibodies. Raising the […]
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Evidence mounts that people with breakthrough infections can spread Delta easily.
Evidence mounts that people with breakthrough infections can spread Delta easily – National Geographic Original study: Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent – Wisconsin, July 2021 – medRxiv Commentary on Twitter The evidence that supports Delta breakthrough infections ability to spread (and why fully vaccinated people need to […]
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[Preprint] Study shows symptomatic breakthrough infections are probably less transmissible than SARS-CoV-2 infections in unvaccinated individuals.
Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine-breakthrough infections: a multi-center cohort study – medRxiv Commentary on Twitter (thread – click for more) Did you hear vaccinated people with Delta “have just as much virus in their nose so are just as infectious as unvaccinated”? Turns out vaccinated people have significantly less culturable […]
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RCT: Awake prone positioning reduces the need for intubation in patients with COVID-19.
Awake prone positioning for COVID-19 acute hypoxaemic respiratory failure: a randomised, controlled, multinational, open-label meta-trial – The Lancet Respiratory Medicine Invited commentary: Awake prone positioning in COVID-19: is tummy time ready for prime time? Related: RCT: Awake prone positioning in patients with hypoxemic respiratory failure due to COVID-19 – no difference in intubation rates compared […]
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