Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA (free for a limited period) Related: M-A of randomized trials: Conservative oxygen therapy for critically ill patients. Oxygen administration for patients with ARDS – Journal of Intensive Care Randomized trial: Similar outcomes with lower vs. […]
The post RCT: Among critically ill patients, targeting oxygenation to a low-normal range vs. high-normal range did not result in a reduction in organ dysfunction. appeared first on Links Medicus.
Why is a third COVID-19 vaccine dose important for people who are immunocompromised? – The Conversation Related: FDA authorizes additional Covid-19 vaccine dose for certain immunocompromised individuals – Other fully vaccinated individuals do not need an additional vaccine dose right now. RCT: third dose of Moderna mRNA vaccine increases immunity in transplant recipients. Study: Among kidney transplant […]
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Study: Patients, not staff, source of most hospital COVID spread – CIDRAP Original article: Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections – eLife
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COVID may be most infectious 2 or 3 days around symptom onset – CIDRAP Original article: COVID-19 Transmission Dynamics Among Close Contacts of Index Patients With COVID-19: A Population-Based Cohort Study in Zhejiang Province, China – JAMA Internal Medicine
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BNT162b2 vaccine booster dose protection: A nationwide study from Israel – medRxiv
The post [Preprint] Pfizer vaccine booster dose protection: A nationwide study from Israel – “Twelve days or more after the booster dose we found an 11.4-fold decrease in the relative risk of confirmed infection, and a >10-fold decrease in the relative risk of severe illness”. appeared first on Links Medicus.
Influenza Vaccination after Myocardial Infarction: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial – Circulation Commentaries: IAMI: Influenza Vaccine Beneficial for Post-MI Patients – TCTMD Influenza Vaccination After Myocardial Infarction – IAMI – American College of Cardiology Flu vaccine after heart attack reduces risk of death – Cardiovascular Business Commentary on Twitter The IAMI trial showed […]
The post #ESCCongress – RCT: Influenza vaccination early after a myocardial infarction (MI) or in high-risk coronary heart disease resulted in a lower risk of a composite of all-cause death, MI, or stent thrombosis compared with placebo. appeared first on Links Medicus.
Rapid Antigen Test Combined with Chest Computed Tomography to Rule Out COVID-19 in Patients Admitted to the Emergency Department – Journal of Clinical Medicine
The post Cohort study: A strategy combining a rapid antigen test and chest CT was effective in ruling out COVID-19 in the emergency department. appeared first on Links Medicus.
Comparison of SARS-CoV-2 Antibody Response Following Vaccination With BNT162b2 and mRNA-1273 – JAMA Related: Moderna may be superior to Pfizer against Delta variant — breakthrough odds rise with time. [Preprint] Pfizer vs. Moderna COVID-19 vaccine effectiveness against the Delta variant in Qatar – Effectiveness against symptomatic disease due to Delta was 53.5% for Pfizer and […]
The post Study demonstrates a significantly higher humoral immunogenicity induced by the SARS-CoV-2 Moderna vaccine compared with the Pfizer- BioNTech vaccine. appeared first on Links Medicus.
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices, United States, 2021–22 Influenza Season – Centers for Disease Control and Prevention Related: Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the United States – Centers for Disease Control and Prevention Commentary: Flu shot and a […]
The post New CDC Guidance says influenza and Covid vaccines can be given together – “COVID-19 vaccines and other vaccines may now be administered without regard to timing” appeared first on Links Medicus.
Factors Associated With Household Transmission of SARS-CoV-2: An Updated Systematic Review and Meta-analysis – JAMA Network Open Commentary: 1 in 5 people with COVID-19 pass it to others in household, study finds – UPI Commentary on Twitter The findings of this meta-analysis suggest that the household remains an important site of #SARSCoV2 transmission, and […]
The post M-A: Factors associated with household transmission of SARS-CoV-2 – recent studies showed higher household secondary attack rates than earliest reports (13.4% vs. 31.1%); more transmissible variants and vaccines may lead to further changes. appeared first on Links Medicus.