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Place du montelukast dans le traitement de l’asthme persistant léger à modéré


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Introduction: Un anti-inflammatoire est recommandé en cas d’asthme persistant. Si les corticoïdes inhalés (CI) restent la référence, des alternatives sont préconisées. Parmi celles-ci, l’antagoniste des récepteurs aux leucotriènes (montelukast) est proposé en monothérapie ou en association aux CI.

État des connaissances: En monothérapie, il est efficace pour contrôler l’asthme d’effort. Dans un contexte d’asthme persistant léger, montelukast est aussi efficace qu’un CI à faible dose. Associé à un CI, montelukast est aussi efficace que les CI à double posologie pour contrôler un asthme persistant modéré.

Conclusions: Son efficacité clinique, sa bonne tolérance et son observance excellente permettent de valider montelukast, pour le traitement des asthmes...

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Use and feasibility of delayed prescribing for respiratory tract infections: A questionnaire survey

Conclusion: Most patients and GPs are satisfied with the delayed prescribing strategy. The patients' age, symptoms and malaise are more important than the diagnosis in predicting antibiotic consumption. The GP's view of the method as a reasonable approach depends on the patient's diagnosis. In our setting, delayed prescribing seems to be a feasible strategy, especially in cases of sinusitis and otitis. Educational efforts to promote delayed prescribing in similar settings should focus on these diagnoses. (Source: BMC Family Practice)

American Thoracic Society Reports On Late-Breaking Clinical Trials

Results from C91 "Late-Breaking Clinical Trials" on Tuesday afternoon, May 17, brought new light to clinical problems and potential treatments. While five examine possible new therapies for people with asthma (pregnant women), emphysema, lymphangioleiomyomatosis (LAM), TB and chronic obstructive pulmonary disease (COPD), a sixth looks at the safety of physician- vs. nurse-led transport teams for critically ill patients, In one, researchers from Australia identified a way for pregnant women with asthma to avoid exacerbations... (Source: Health News from Medical News Today)

Cardiopulmonary Exercise Testing in the Assessment of Pulmonary Hypertension

Exercise testing continues to be a useful tool to diagnose PAH and secondary PAH. Expert Review of Respiratory Medicine (Source: Medscape Today Headlines)

Sun Protects Against Childhood Asthma

Vitamin D, which is primarily absorbed from the sun, plays a role in protection against childhood asthma. Now, a new study led by Valencian researchers has shown that children who live in colder, wetter cities are at greater risk of suffering from this respiratory problem, since there are fewer hours of sunlight in such places. "Prolonged exposure to the sun can cause cancer, but it's also dangerous to avoid it... (Source: Health News from Medical News Today)

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