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MERS-CoV Easily Spreads In Hospitals

A team of experts who traveled to Saudi Arabia have reported that the new Middle East respiratory syndrome coronavirus (MERS-CoV) is easily transmitted in healthcare settings, posing a serious public health threat. The researchers from Johns Hopkins University studied how the virus spread in four different Saudi hospitals. They published their findings in The New England Journal of Medicine.

MERS-CoV is much deadlier than the coronavirus responsible for the severe acute respiratory syndrome (SARS) in 2003, the authors wrote...

Study Evaluates Procedures For Diagnosing Sarcoidosis

Among patients with suspected stage I/II pulmonary sarcoidosis who were undergoing confirmation of the condition via tissue sampling, the use of the procedure known as endosonographic nodal aspiration compared with bronchoscopic biopsy, the current diagnostic standard, resulted in greater diagnostic yield, according to a study in the June 19 issue of JAMA.

Sarcoidosis, a disease that causes granulomas (usually small masses) due to chronic inflammation in body tissues, has an estimated lifetime risk of 1 percent to 2 percent...

Costs of COPD in Relation to Compliance With GuidelinesCosts of COPD in Relation to Compliance With Guidelines

What are the economic effects of non-adherence to the GOLD guidelines in COPD management? Therapeutic Advances in Respiratory Disease

Study Reveals How New Respiratory Virus Spreads

Infectious-disease experts went to Middle East to gather information on often deadly MERS virus

Chronic Obstructive Pulmonary Disease: Official diagnosis and treatment guidelines of the Czech Pneumological and Phthisiological Society; a novel phenotypic approach to COPD with patient-oriented care.

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COPD is a global concern. Currently, several sets of guidelines, statements and strategies to managing COPD exist around the world.

METHODS: The Czech Pneumological and Phthisiological Society (CPPS) has commissioned an Expert group to draft recommended guidelines for the management of stable COPD. Subsequent revisions were further discussed at the National Consensus Conference (NCC). Reviewers' comments contributed to the establishment of the document's final version.

DIAGNOSIS: The hallmark of the novel approach to COPD is the integrated evaluation of the patient's lung functions, symptoms, exacerbations and identifications of clinical phenotype(s). The CPPS defines 6 clinically relevant phenotypes: frequent exacerbator, COPD-asthma overlap, COPD-bronchiectasis overlap, emphysematic phenotype, bronchitic phenotype and pulmonary cachexia phenotype.

TREATMENT: Treatment recommendations can be divided into four steps.

  • 1(st) step = Risk exposure elimination: reduction of smoking and environmental tobacco smoke (ETS), decrease of home and occupational exposure risks.
  • 2(nd) step = Standard treatment: inhaled bronchodilators, regular physical activity, pulmonary rehabilitation, education, inhalation training, comorbidity treatment, vaccination.
  • 3(rd) step = Phenotype-specific therapy: PDE4i, ICS+LABA, LVRS, BVR, AAT augmentation, physiotherapy, mucolytic, ABT.
  • 4(th) step = Care for respiratory insufficiency and terminal COPD: LTOT, lung transplantation, high intensity-NIV and palliative care.

CONCLUSION: Optimal treatment of COPD patients requires an individualised, multidisciplinary approach to the patient's symptoms, clinical phenotypes, needs and wishes. The new Czech COPD guideline reflects and covers these requirements.

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