Abstract Chronic rhinosinusitis (CRS) is a prevalent inflammatory disorder of the paranasal mucosa, which encompasses a complex and heterogeneous disease population with variable pathophysiologic, host, and environmental etiologies. Due to this variability and an evolving understanding of its underlying etiology, successful medical and surgical management cannot be standardized and remains challenging. Medical management remains the first line strategy for this chronic condition with no known cure. Surgical therapy remains an important adjunct intervention when medical therapy fails to control the disease adequately. An up-to-date review of evidence-based recommendations, as well as emerging treatment strategies in the management of CRS follows. (Source: Current Respiratory Care R...

Abstract Fibrotic hypersensitivity pneumonitis (FHP) is a specific form of HP defined by chest imaging evidence or pathologic evidence of fibrosis or scarring. Fibrotic HP appears to be irreversible, is often progressive and frequently indistinguishable from other forms of chronic fibrosing interstitial lung diseases (ILD), in particular idiopathic pulmonary fibrosis (IPF). Accurate diagnosis is a challenge given the diverse and often nonspecific clinicoradiologic patterns, heterogenous clinical course, and a frequent lack of a readily recognizable temporal relationship between exposure to an inciting antigen (IA) and symptoms in more than half of the patients. This chapter focuses on the clinical features, diagnostic evaluation and management of FHP. (Source: Current Respiratory ...

In conclusion, a Q scan without a V scan, when properly interpreted according to the prospective investigative study of acute pulmonary embolism diagnosis methodology (presence or absence of wedge-shaped perfusion defects) and combined with the formulation of a pre-test clinical probability, can be used in most patients with clinical suspicion of PE, reducing costs and radiation load, increasing the practicality of the examination, and providing diagnostic accuracy comparable to that of CT angiography. (Source: Clinical and Translational Imaging)

The title “Is respiratory protection appropriate in the Ebola response?” suggests that a critically important hypothesis regarding transmission of Ebola will be discussed. Instead, in their Letter, the authors assert that direct contact precautions advocated by the US Centers for Disease Control and Prevention, are sufficient, and argue against more conservative infection control measures. Despite their insistence that conservative respiratory precautions are not needed, such measures are publicly and repeatedly shown during the repatriation of infected health-care workers to specially equipped medical centres, rather than to any hospital practising direct contact precautions, reinforcing a serious inconsistency between recommendations and practice. (Source: LANCET)