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Treatment of sarcoidosis-associated pulmonary hypertension: A single centre retrospective experience using targeted therapies.

CONCLUSIONS: Our results suggest that targeted therapies are safe in  patients with SAPH. Controlled trials are warranted before therapeutic recommendations can be made. PMID: 25078636 [PubMed - in process] (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)

The value of chest radiograph and computed tomography in pulmonary sarcoidosis.

Authors: Greco FG, Spagnolo P, Muri M, Paladini I, Chizzolini F, Piciucchi S, Colombi D, Sverzellati N Abstract Imaging makes a significant contribution to the diagnosis, prognosis and follow-up in sarcoidosis. Despite its increasing use, the role of computed tomography (CT) scanning in patients with known or suspected pulmonary sarcoidosis is still undefined. This review aims to compare the utility and limitations of chest radiograph and CT in patients with pulmonary sarcoidosis, with regards to the most critical clinical issues such as the diagnostic sensitivity, the differential diagnosis, and the prediction of the disease reversibility. PMID: 25078638 [PubMed - in process] (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)

Surgical lung biopsy for the diagnosis of interstitial lung disease: a review of the literature and recommendations for optimizing safety and efficacy.

Authors: Nguyen W, Meyer KC Abstract Making an accurate diagnosis of a specific type of interstitial lung disease (ILD) requires a structured and comprehensive approach that includes a complete patient history, careful physical examination, appropriate laboratory testing, and thoracic imaging. If invasive procedures are required, bronchoscopy with bronchoalveolar lavage (BAL) and/or endoscopic lung biopsy (ELB) can frequently establish a confident diagnosis. However, surgical lung biopsy (SLB) may be required to make a confident diagnosis. Because SLB may be associated with a significant risk of morbidity and mortality, we performed a comprehensive literature review of all available literature published in the English language that reported outcomes of surgical lung biopsy performe...

The effect of anticoagulant therapy for idiopathic pulmonary fibrosis in real life practice.

Conclusion: In this retrospective study patients treated with anticoagulants had a worse survival and a shorter interval to disease progression. This support the recent finding that warfarin worsen the respiratory status and survival of IPF patients. PMID: 24071883 [PubMed - in process] (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)

Outcome of patients with interstitial lung disease admitted to the intensive care unit.

Conclusion: This study, while confirming the poor prognosis of FIIP patients in ICU, highlights the better prognosis of DI-ILD and M-ILD even though severity criteria on admission are similar in these 3 groups. These data impact on the management of these patients in ICU in whom a proper diagnostic of the underlying condition is crucial. PMID: 24071885 [PubMed - in process] (Source: Sarcoidosis Vasculitis and Diffuse Lung Diseases)

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