Two large populational-based studies find a slightly increased risk of thrombotic events following AstraZeneca COVID-19 vaccination.
Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, or thrombocytopenic events: A population-based cohort study of 46 million adults in England – PLOS Medicine See also: First dose ChAdOx1 and BNT162b2 COVID-19 vaccinations and cerebral venous sinus thrombosis: A pooled self-controlled case series study of 11.6 million individuals in England, Scotland, and […]
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M-A: Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections.
Diagnostic accuracy of point-of-care tests in acute community-acquired lower respiratory tract infections. A systematic review and meta-analysis – Clinical Microbiology and Infection
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[Preprint] A large-scale observational study in Chile found CoronaVac (an inactivated SARS-CoV-2 vaccine) was associated with an effectiveness of 74.5% against infection, 91.0% against hospitalization, and 93.8% against ICU admission in children aged 6 to
Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Children and Adolescents: A Large-Scale Observational Study – Preprints with The Lancet Commentary: Full schedule of CoronaVac vaccine shown to be highly effective in children – News Medical
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Meta-analysis finds low risk of a second allergic reaction to SARS-CoV-2 mRNA vaccines in patients with an allergic reaction with the first dose.
Risk of Second Allergic Reaction to SARS-CoV-2 Vaccines: A Systematic Review and Meta-analysis – JAMA Internal Medicine Commentary on Twitter Systematic review and meta-analysis of 22 studies and 1366 patients found that there was a low risk of repeat allergic reaction to a second #COVID19 mRNA vaccine dose in people who had immediate allergic […]
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Opinion by Dr. Eric Topol | Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed.
Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed – The Guardian Commentary from the author on Twitter (thread – click for more) My new essay @guardian "Why one-shot after a Covid-19 infection should suffice to be considered fully-vaxxed"https://t.co/RaBUpET2CZSummarizes extensive new evidence that confirmed Prior Covid ("Natural Immunity" or NI) + […]
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Review: Cancer-associated venous thromboembolism.
Cancer-associated venous thromboembolism – Nature Reviews Disease Primers (if the link is paywalled, try this one) Infographic: Cancer-associated venous thromboembolism – Nature Reviews Disease Primers (if the link is paywalled, try this one) Related: NCCN Guideline: Cancer-Associated Venous Thromboembolic Disease. ASH 2021 guidelines for prevention and treatment of venous thromboembolism in patients with cancer Review: […]
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ESCMID rapid guidelines for assessment and management of long COVID.
ESCMID rapid guidelines for assessment and management of long COVID – Clinical Microbiology and Infection Related: ERS statement on Long COVID-19 follow-up. Proposed subtypes of long-Covid and their respective potential therapies. EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation. Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians. Global surveillance, research, and collaboration […]
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RCT: In patients with mild to moderate Covid-19 and comorbidities, treatment with Ivermectin did not reduce the risk of disease progression.
Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial – JAMA Internal Medicine Commentaries: Ivermectin doesn’t prevent severe disease from Covid-19, new study finds – CNN Ivermectin futile for mild to moderate COVID-19, study finds – CIDRAP Related: Case Series: Toxic effects from […]
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WHO Interim Guidance: Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant.
Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant: interim guidance – World Health Organization Commentary on Twitter (thread – click for more) #COVID19 quarantine period may be shortened for contacts who test negative on a PCR or antigen based rapid diagnostic test. Quarantine can be shortened, for example to seven […]
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Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.
Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada – JAMA
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