RCT: In patients with mild to moderate Covid-19 and comorbidities, treatment with Ivermectin did not reduce the risk of disease progression.
Efficacy of Ivermectin Treatment on Disease Progression Among Adults With Mild to Moderate COVID-19 and Comorbidities: The I-TECH Randomized Clinical Trial – JAMA Internal Medicine Commentaries: Ivermectin doesn’t prevent severe disease from Covid-19, new study finds – CNN Ivermectin futile for mild to moderate COVID-19, study finds – CIDRAP Related: Case Series: Toxic effects from […]
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WHO Interim Guidance: Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant.
Contact tracing and quarantine in the context of the Omicron SARS-CoV-2 variant: interim guidance – World Health Organization Commentary on Twitter (thread – click for more) #COVID19 quarantine period may be shortened for contacts who test negative on a PCR or antigen based rapid diagnostic test. Quarantine can be shortened, for example to seven […]
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Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.
Estimates of SARS-CoV-2 Omicron Variant Severity in Ontario, Canada – JAMA
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SIMEU position paper on non-invasive respiratory support in COVID-19 pneumonia.
SIMEU position paper on non-invasive respiratory support in COVID-19 pneumonia – Internal and Emergency Medicine Related: RCT: CPAP improved outcomes in patients with acute hypoxemic respiratory failure due to COVID-19, but high-flow nasal oxygen was not better than conventional oxygen therapy. RCT: In patients with severe Covid-19, high-flow oxygen therapy reduced the likelihood of invasive […]
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Cohort study: Protection against SARS-CoV-2 after Covid-19 vaccination lasts longer in patients with previous infection.
Protection against SARS-CoV-2 after Covid-19 Vaccination and Previous Infection – New England Journal of Medicine
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RCT: Oral Nirmatrelvir for high-risk adults with Covid-19 reduces the risk of hospitalization by 89%.
Oral Nirmatrelvir for High-Risk, Nonhospitalized Adults with Covid-19 – New England Journal of Medicine Audio Interview: A New Antiviral against Covid-19 – new England Journal of Medicine Related: [Press release – not published yet] Pfizer’s Covid pill remains 89% effective for reducing the risk of hospitalization or death in final analysis. [Press release – not […]
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Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis.
Prone positioning during venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome: a pooled individual patient data analysis – Critical Care
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Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysis.
Veno-venous extracorporeal membrane oxygenation (vv-ECMO) for severe respiratory failure in adult cancer patients: a retrospective multicenter analysis – Journal of Intensive Care Commentary on Twitter VV #ECMO in adults with cancer developing severe respiratory failure: survival remains poor, no significant advantage, carefully select! Low PLT, elevated lactate, disease status: adverse prognostic factors to be […]
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Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study.
Diagnosis of deep vein thrombosis with D-dimer adjusted to clinical probability: prospective diagnostic management study – The BMJ
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Covid-19: Fourth vaccine doses—who needs them and why?
Covid-19: Fourth vaccine doses—who needs them and why? – The BMJ
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