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RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.

Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children – New England Journal of Medicine News Release: Treatment length reduced for children with tuberculosis – University College London   Commentary on Twitter Completing 6 months of treatment for tuberculosis in children is a challenge. In this open-label trial involving 1204 children in sub-Saharan Africa […]

The post RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months. appeared first on Links Medicus.

RCT: Reliever-triggered inhaled glucocorticoid reduces severe exacerbations in black and latinx adults with moderate-to-severe asthma.

Reliever-Triggered Inhaled Glucocorticoid in Black and Latinx Adults with Asthma – New England Journal of Medicine (link to abstract – $ for full-text) Commentary: Patient-centered intervention improved asthma outcomes for Black and Latinx adults – Brigham and Women’s Hospital  

The post RCT: Reliever-triggered inhaled glucocorticoid reduces severe exacerbations in black and latinx adults with moderate-to-severe asthma. appeared first on Links Medicus.

Pictorial Review | Extrapulmonary tuberculosıs: an old but resurgent problem.

Extrapulmonary tuberculosıs: an old but resurgent problem – Insights into Imaging  

The post Pictorial Review | Extrapulmonary tuberculosıs: an old but resurgent problem. appeared first on Links Medicus.

RCT: Combination treatment with Varenicline and Nicotine patch may increase smoking cessation rates among smokers who drink heavily.

Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily: A Randomized Clinical Trial – JAMA Network Open Commentary: Combination treatment is effective for treating smokers who drink heavily – University of Chicago Medical Center   Commentary on Twitter In this RCT, the combination of varenicline + nicotine […]

The post RCT: Combination treatment with Varenicline and Nicotine patch may increase smoking cessation rates among smokers who drink heavily. appeared first on Links Medicus.

Case report: Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices.

Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices – Canadian Medical Association Journal  

The post Case report: Nonthrombotic pulmonary embolism secondary to cyanoacrylate embolization of gastric varices. appeared first on Links Medicus.

Study shows the number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance”.

News Release: Number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance,” warn experts – BMJ Original Study: SARS-CoV-2 antigen lateral flow tests for detecting infectious people: linked data analysis – The BMJ Commentaries: Lateral flow tests may be missing ‘substantial’ number of COVID-19 infections – Imperial College London […]

The post Study shows the number of covid-19 infections missed by lateral flow tests “substantial enough to be of clinical importance”. appeared first on Links Medicus.

RCT: Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions.

Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions (SIMPLE): an open-label, randomised controlled trial – The Lancet Respiratory Medicine (link to abstract – $ for full-text)   Commentary on Twitter Thoracic ultrasonography-guided pleurodesis in patients with malignant pleural effusions results in shorter hospital stay without reducing the success rate of the procedure […]

The post RCT: Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions. appeared first on Links Medicus.

Systematic Review: Anticoagulants for people hospitalized with COVID‐19.

Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library Summary: Do blood thinners prevent people who are hospitalised with COVID-19 from developing blood clots? – Cochrane Library Related: Anticoagulation in Patients With COVID-19: JACC Review Topic of the Week.  

The post Systematic Review: Anticoagulants for people hospitalized with COVID‐19. appeared first on Links Medicus.

Arterial blood gas analysis: as safe as we think? A multicentre historical cohort study.

Arterial blood gas analysis: as safe as we think? A multicentre historical cohort study – ERJ Open  

The post Arterial blood gas analysis: as safe as we think? A multicentre historical cohort study. appeared first on Links Medicus.

Updated WHO guidance conditionally recommends Molnupiravir for patients with non-severe covid-19 at highest risk of hospitalization.

BMJ News Release: WHO recommends antiviral drug for patients with non-severe covid-19 at highest risk of hospital admission – BMJ WHO News Release: WHO updates its treatment guidelines to include molnupiravir See updated guidance: A living WHO guideline on drugs for covid-19 – BMJ Related: Editorial (just published): Molnupiravir’s authorisation was premature – The BMJ […]

The post Updated WHO guidance conditionally recommends Molnupiravir for patients with non-severe covid-19 at highest risk of hospitalization. appeared first on Links Medicus.