Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine (link to abstract – $ for full-text)   Commentary on Twitter Even though supplemental oxygen is used for the treatment of patients with hypoxemic respiratory failure, the most effective oxygenation targets are not known. In this randomized trial, a […]

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Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis – JAMA Internal Medicine Related: The Sensitivity and Costs of Testing for SARS-CoV-2 Infection With Saliva Versus Nasopharyngeal Swabs: A Systematic Review and Meta-analysis – Annals of Internal Medicine  

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Covid-19: What new variants are emerging and how are they being investigated? – The BMJ  

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Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study – The Lancet Respiratory Medicine Commentaries: Improving clinical management of COVID-19: the role of prediction models – The Lancet Respiratory Medicine Tool identifies COVID-19 patients at highest risk of deterioration – UK Research and Innovation See calculator: […]

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COVID-19 Diagnostic Guidelines Updates (Jan. 16, 2021) – Infectious Diseases Society of America  

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Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes – Critical Care Related meta-analysis: Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials – Journal of Cardiothoracic and Vascular Anesthesia  

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Knowledge translation tools to guide care of non-intubated patients with acute respiratory illness during the COVID-19 Pandemic – Critical Care  

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Initiating Pharmacologic Treatment in Tobacco-Dependent Adults – JAMA (free for a limited period) Author Interview: Pharmacologic Management of Tobacco Cessation Original Guideline: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults. An Official American Thoracic Society Clinical Practice Guideline – American Journal of Respiratory and Critical Care Medicine  

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Interventions for Tobacco Smoking Cessation in Adults, Including Pregnant Persons – U.S. Preventive Services Task Force Editorial: A Comprehensive Approach to Increase Adult Tobacco Cessation – JAMA Author Interview: USPSTF Recommendation: Tobacco Cessation in Adults JAMA Patient Page: Interventions to Promote Tobacco Cessation  

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Prophylaxis for COVID-19: a systematic review – Clinical Microbiology and Infection  

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