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Case series: therapeutic plasma exchange in 3 patients with vaccine-induced immune thrombotic thrombocytopenia.

Therapeutic Plasma Exchange in Vaccine-Induced Immune Thrombotic Thrombocytopenia – New England Journal of Medicine   Commentary on Twitter Three patients with severe manifestations of VITT after #COVID19 vaccination had poor response to initial therapy with anticoagulants and intravenous immune globulin. Their condition improved after therapeutic plasma exchange was initiated. — NEJM (@NEJM) July 7, 2021 […]

The post Case series: therapeutic plasma exchange in 3 patients with vaccine-induced immune thrombotic thrombocytopenia. appeared first on Links Medicus.

Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.

Effectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination […]

The post Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death. appeared first on Links Medicus.

M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.

Systematic review and meta-analysis of randomised controlled trials testing the safety and efficacy of convalescent plasma in the treatment of coronavirus disease 2019 (COVID-19): Evidence-base for practise and implications for research – Transfusion Medicine  

The post M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19. appeared first on Links Medicus.

WHO recommends life-saving interleukin-6 receptor blockers for COVID-19 and urges producers to join efforts to rapidly increase access – “These are the first drugs found to be effective against COVID-19 since corticosteroids were recommended by WHO in Sep

WHO recommends life-saving interleukin-6 receptor blockers for COVID-19 and urges producers to join efforts to rapidly increase access – World Health Organization   Commentary on Twitter (thread – click for more) ? treatment recommendation from WHO:WHO recommends life-saving interleukin-6 receptor blockers to treat #COVID19 and urges producers to join efforts to rapidly increase access. ?https://t.co/h4IcZad2VA […]

The post WHO recommends life-saving interleukin-6 receptor blockers for COVID-19 and urges producers to join efforts to rapidly increase access – “These are the first drugs found to be effective against COVID-19 since corticosteroids were recommended by WHO in September 2020”. appeared first on Links Medicus.

M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients w

Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis – JAMA Editorial: IL-6 Receptor Antagonist Therapy for Patients Hospitalized for COVID-19: Who, When, and How? – JAMA Commentaries: Interleukin-6 antagonists improve outcomes in hospitalised COVID-19 patients – King’s College London AND WHO advises 2 monoclonal antibodies for severe COVID […]

The post M-A: Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19 – “The 4% absolute risk reduction in mortality from 25% to 21% with IL-6 inhibition added to glucocorticoids may not translate to patients with a lower baseline mortality risk and likely do not justify the additional expense and risk for toxicities for patients hospitalized with modest oxygen requirements and a stable clinical course (from editorial)”. appeared first on Links Medicus.

A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19.

A living WHO guideline on drugs for covid-19 – The BMJ   Commentary on Twitter The latest version of this @WHO living guidance provides a strong recommendation for interleukin-6 (IL-6) receptor blockers (tocilizumab or sarilumab) in patients with severe or critical covid-19. Read the updated WHO guideline on drugs for #COVID19 https://t.co/FUb9yzFRwo — The BMJ […]

The post A living WHO guideline on drugs for covid-19 – interleukin-6 receptor blockers are now recommended for patients with severe or critical covid-19. appeared first on Links Medicus.

RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19.

Ivermectin to prevent hospitalizations in patients with COVID-19 (IVERCOR-COVID19) a randomized, double-blind, placebo-controlled trial – BMC Infectious Diseases Commentary: Ivermectin: balance of evidence shows no significant benefit against Covid-19 – MSN News Related: Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials – “IVM did not reduce all-cause mortality, […]

The post RCT: Ivermectin does not prevent hospitalizations in patients with COVID-19. appeared first on Links Medicus.

Choosing Wisely for COVID-19: ten evidence-based recommendations for patients and physicians.

Choosing Wisely for COVID-19: ten evidence-based recommendations for patients and physicians – Nature Medicine  

The post Choosing Wisely for COVID-19: ten evidence-based recommendations for patients and physicians. appeared first on Links Medicus.

Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO.

Joint COVAX Statement on the Equal Recognition of Vaccines – World Health Organization   Commentary on Twitter (thread – click for more) #COVAX urges all government authorities to recognize as fully vaccinated all who have received #COVID19 vaccines approved by WHO or one of 11 approved Stringent Regulatory Authorities, when making decisions on who is […]

The post Joint COVAX Statement on the Equal Recognition of Vaccines – COVAX urges all government authorities to recognize as fully vaccinated all people who have received COVID-19 vaccines that have been deemed safe and effective by WHO. appeared first on Links Medicus.

CDC Report: Underlying medical conditions and severe illness among 540,667 adults hospitalized with COVID-19, March 2020–March 2021.

Underlying Medical Conditions and Severe Illness Among 540,667 Adults Hospitalized With COVID-19, March 2020–March 2021 – Centers for Disease Control and Prevention   Commentary on Twitter A new report finds that obesity, diabetes with complication, and the presence of multiple chronic conditions were the strongest chronic risk factors for death from #COVID19 among hospitalized adults. […]

The post CDC Report: Underlying medical conditions and severe illness among 540,667 adults hospitalized with COVID-19, March 2020–March 2021. appeared first on Links Medicus.