Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials – The Lancet (link to abstract – $ for full-text) Commentary on Twitter For refractory chronic cough or unexplained chronic cough, gefapixant 45 mg twice […]
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Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine
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Clinical care of severe acute respiratory infections – Tool kit – World Health Organization Commentary on Twitter (thread – click for more) Updated toolkit for the clinical care of severe acute respiratory infections including: ? severe #pneumonia? acute respiratory distress syndrome? sepsis & septic shock ? https://t.co/ROvKZz12LT pic.twitter.com/LdcNJiJcxA — World Health Organization (WHO) (@WHO) […]
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Thrombosis patterns and clinical outcome of COVID-19 vaccine-induced immune thrombotic thrombocytopenia: A Systematic Review and Meta-Analysis – International Journal of Infectious Diseases Related: Case series of Thrombosis with Thrombocytopenia Syndrome after Covid-19 vaccination in the US. Review: Vaccine-induced immune thrombotic thrombocytopenia. Vaccine induced immune thrombocytopenia and thrombosis: summary of NICE guidance. Clinical features of vaccine-induced […]
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Effect of High-Flow Nasal Cannula Therapy vs Continuous Positive Airway Pressure Following Extubation on Liberation From Respiratory Support in Critically Ill Children: A Randomized Clinical Trial – JAMA (free for a limited period) Editorial: Selecting Intermediate Respiratory Support Following Extubation in the Pediatric Intensive Care Unit – JAMA (free for a limited period) News Release: […]
The post RCT: In critically ill children requiring noninvasive respiratory support following extubation, high-flow nasal cannula therapy was NOT noninferior to CPAP, resulting in increased time to liberation from respiratory support. appeared first on Links Medicus.
How to do lung ultrasound – European Heart Journal – Cardiovascular Imaging
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Diagnostic performance of CO-RADS for COVID-19: a systematic review and meta-analysis – European Radiology Related: CO-RADS – A categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation – Radiology
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Studying severe long COVID to understand post-infectious disorders beyond COVID-19 – Nature Medicine Related: Review: Post-acute COVID-19 syndrome. ESCMID rapid guidelines for assessment and management of long COVID. ERS statement on Long COVID-19 follow-up. Proposed subtypes of long-Covid and their respective potential therapies. EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation. Addressing Post-COVID […]
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Pulse Oximetry for Monitoring Patients with Covid-19 at Home — A Pragmatic, Randomized Trial – New England Journal of Medicine Commentary on Twitter A potential practice changer by @kit_delgadoMD et al in NEJM today. At-home pulse oximeters did NOT improve outcomes. Important to focus on things that help. If these devices don't help, then […]
The post Pragmatic RCT: In outpatients with Covid-19, the addition of pulse oximetry for monitoring did not improve outcomes compared to subjective assessments of dyspnea alone. appeared first on Links Medicus.
Fluvoxamine for Outpatient Management of COVID-19 to Prevent Hospitalization: A Systematic Review and Meta-analysis – JAMA Network Open Commentary: Common Antidepressant Likely Cuts Risk Of Covid Hospitalization, Study Finds – Forbes Related: Short Review: Fluvoxamine for symptomatic outpatients with COVID-19. Fluvoxamine for Covid-19: What Prescribers and Pharmacists Need to Know. Fluvoxamine for the early treatment […]
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