Asthma drug budesonide shortens recovery time in non-hospitalised patients with COVID-19 – PRINCIPLE / University of Oxford Original study (preprint): Inhaled budesonide for COVID-19 in people at higher risk of adverse outcomes in the community: interim analyses from the PRINCIPLE trial – medRxiv Commentary: Covid: Asthma drug ‘speeds up recovery at home’ – BBC Related […]
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SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN) – The Lancet Commentary: Correlates of protection from SARS-CoV-2 infection – The Lancet Commentary on Twitter ?SIREN STUDY? @TheLancet Previous SARS-CoV-2 infectionprovides protection similar to or even better than currently used vaccines ?84% risk reduction(RR) […]
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Post-extubation oxygenation strategies in acute respiratory failure: a systematic review and network meta-analysis – Critical Care
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Chinese COVID-19 vaccine maintains protection in variant-plagued Brazil – Science Original study: [Preprint] CoronaVac is 50% effective for reducing symptomatic SARS-CoV-2 infection after the first dose in the setting of high P.1 variant transmission in Brazil (study and commentary on Twitter)
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Japanese doctors perform world’s first living donor lung transplant to a Covid-19 patient – CNN
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EMA Reviews Link Between Blood Clots and Johnson & Johnson Vaccine – Health Policy Watch See also: Johnson & Johnson’s COVID-19 vaccine under scrutiny at EMA after 4 ‘serious cases’ of unusual blood clots – Fierce Pharma AND J&J COVID-19 vaccine under EU review over blood clots, AstraZeneca probe grows – Reuters
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Efficacy and Safety of a COVID-19 Inactivated Vaccine in Healthcare Professionals in Brazil: The PROFISCOV Study – SSRN Commentary on Twitter (thread – click for more) Preprint on Brazilian trial by @butantanoficial of Sinovac's CoronaVac, 2 weeks apart. Data for 9,823 people who had 2 doses, 12,396 after 1 dose.The P1 ("Brazilian") variant of […]
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Papers Confirm Rare Thrombocytopenia Link to AstraZeneca Vaccine – TCTMD Study 1: Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination – New England Journal of Medicine Study 2: Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination – New England Journal of Medicine
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Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients – Critical Care Commentary on Twitter Prone position in #COVID19, use & effect:➡️PP widely adopted, the more severe the respiratory failure, the more frequent the use➡️PP improved oxygenation in most (better V/Q matching?)➡️mortality of O2-Non-Responders significantly higher@Crit_Care […]
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Inhaled budesonide in the treatment of early COVID-19 (STOIC): a phase 2, open-label, randomised controlled trial – The Lancet Respiratory Medicine Commentary: Early treatment with inhaled budesonide to prevent clinical deterioration in patients with COVID-19 – The Lancet Respiratory Medicine Commentary on Twitter NEW Research— Early administration of inhaled budesonide reduced the likelihood of […]
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