Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients – Critical Care
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An adaptive randomized controlled trial of non-invasive respiratory strategies in acute respiratory failure patients with COVID-19 – medRxiv Commentary: Covid: Pressured oxygen reduces ventilator need – BBC Commentary on Twitter (thread – click for more) RECOVERY-RS results out, and confirm what most of us have been doing: CPAP reduces intubation/mortality by 28% compared with […]
The post [Preprint] RCT: non-invasive respiratory strategies in acute respiratory failure in patients with COVID-19 – CPAP reduced the composite outcome of intubation or death within 30 days; high-flow nasal oxygenation was not associated with better outcomes. appeared first on Links Medicus.
Percutaneous dilatational tracheotomy in high-risk ICU patients – Annals of Intensive Care
The post International, multicenter observational study: Outcomes with percutaneous dilatational tracheotomy in high-risk ICU patients. appeared first on Links Medicus.
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 – New England Journal of Medicine Editorial: Surviving Covid-19 with Heparin? Commentaries: Full-dose blood thinners reduce the need for organ support in moderately ill COVID-19 patients, but not in critically ill patients – National Institutes of Health Therapeutic-Dose Heparin in COVID-19: Who Benefits, Who Doesn’t […]
The post RCT: In noncritically ill patients hospitalized with Covid-19, therapeutic-dose anticoagulation with heparin increased the probability of survival to hospital discharge compared with usual-care thromboprophylaxis. appeared first on Links Medicus.
Lung transplantation for interstitial lung disease – European Respiratory Review
The post Review: Lung transplantation for interstitial lung disease. appeared first on Links Medicus.
Tuberous sclerosis complex for the pulmonologist – European Respiratory Review
The post Review: Tuberous sclerosis complex for the pulmonologist. appeared first on Links Medicus.
SARS-CoV-2 Variants in Patients with Immunosuppression – New England Journal of Medicine Commentary on Twitter In the pandemic, immunocompromised people (~3% of Americans) are not getting adequate recognition for the potential of in-host evolution of the virus (highlighted studies) and the need for far better approaches to protect them https://t.co/XDT1VxC9ZK @NEJM pic.twitter.com/ciw1WD9EzC — Eric […]
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Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 – New England Journal of Medicine Related: RCT: Bamlanivimab plus Etesevimab reduce mortality and hospitalization in ambulatory patients with early Covid-19 (within 3 days of a positive test) who are at risk for clinical deterioration (i.e., older people, obese, diabetics, immunocompromised, with CV disease). [Preprint] RECOVERY trial finds […]
The post RCT: Subcutaneous REGEN-COV antibody combination prevented symptomatic Covid-19 infection in previously uninfected household contacts of infected persons. appeared first on Links Medicus.
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 – New England Journal of Medicine Editorial: Surviving Covid-19 with Heparin? Commentaries: Full-dose blood thinners reduce the need for organ support in moderately ill COVID-19 patients, but not in critically ill patients – National Institutes of Health Therapeutic-Dose Heparin in COVID-19: Who Benefits, Who Doesn’t […]
The post In critically ill patients with Covid-19, therapeutic anticoagulation with heparin did not result in improved outcomes compared to usual-care pharmacologic thromboprophylaxis. appeared first on Links Medicus.
Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset – eLlife Related: Exploring the gap between excess mortality and COVID-19 deaths in 67 countries. Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million […]
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