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RCT: Twice-Yearly Depemokimab Reduced Exacerbations in Severe Eosinophilic Asthma

RCT: Twice-Yearly Depemokimab Reduced Exacerbations in Severe Eosinophilic Asthma

Background: Severe asthma with an eosinophilic phenotype often leads to frequent exacerbations despite treatment with medium- or high-dose inhaled glucocorticoids and additional controllers. Interleukin-5 is pivotal in eosinophil growth and survival, contributing to airway inflammation. Existing biologic therapies targeting interleukin-5 require frequent dosing intervals. Depemokimab is an ultra-long-acting anti–interleukin-5 biologic with enhanced binding affinity, potentially […]

The post RCT: Twice-Yearly Depemokimab Reduced Exacerbations in Severe Eosinophilic Asthma appeared first on Links Medicus.

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