The National Lung Screening Trial (NLST) demonstrated that low-dose computed tomography (LDCT) screening reduced lung cancer mortality by 20% [1]. Lung cancer screening was subsequently recommended by the US Preventive
Protective immunity against Mycobacterium tuberculosis is poorly understood. The role of interleukin (IL)-4, the archetypal T-helper type 2 (Th2) cytokine, in the immunopathogenesis of human tuberculosis remains unclear.
Blood and/or
In this study, our expert panel achieved consensus on 20 items that can be used to guide supplemental oxygen use in patients with fibrotic ILD. We further identified several areas where respondents were unsure or where consensus could not be met, suggesting future areas where research efforts should be focused. Finally, we identified discrepancies between scenarios where clinicians would recommend oxygen and poor patient access, based on regional funding criteria or testing requirements.
The MIST2 (Second Multicentre Intrapleural Sepsis Trial) trial showed that combined intrapleural use of tissue plasminogen activator (t-PA) and recombinant human DNase was effective when compared with single agents or
Although broad knowledge of influenza viral pneumonia has been established, the significance of non-influenza respiratory viruses in community-acquired pneumonia (CAP) and their impact on clinical outcomes remains unclear, especially in