Source: Cochrane Library Area: Evidence > Drug Specific Reviews Background Diffuse panbronchiolitis (DPB) is a chronic airways disease predominantly affecting East Asians. Macrolides, a class of antibiotics, have been used as the main treatment for DPB, based on evidence from retrospective and non-randomised studies.   Objectives To assess the efficacy and safety of macrolides for DPB.   Search strategy We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2010, issue 1), which contains the Cochrane Acute Respiratory Infections Group's Specialised Register, MEDLINE (1966 to April 2010), EMBASE (1974 to April 2010), Chinese Biomedical Literature Database (CBM) (1978 to April 2010), China National Knowledge Infrastructure (CNK...

Adequate levels of physical activity need to be integrated into the daily life of patients with COPD for optimal management. Expert Review of Respiratory Medicine (Source: Medscape Today Headlines)

Denning DW, Van Wye JE, Lewiston NJ, Stevens DA (Source: The Aspergillus Website - articles)

Source: Cochrane Library Area: Evidence > Drug Specific Reviews Background The efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis has not been systematically evaluated.   Objectives To systematically review the efficacy of decongestants, antihistamines and nasal irrigation in children with clinically diagnosed acute sinusitis. We considered the following four interventions: 1) decongestants versus placebo or no medication, 2) antihistamines versus placebo or no medication, 3) decongestant and antihistamine combination versus placebo or no medication, 4) nasal irrigation versus no irrigation. The primary outcomes of the review were symptom resolution (improvement in symptom score from enrolment to day 5) and ov...