Conclusions : Chronic cough due to non‐acid reflux may be related to cough reflex hypersensitivity caused by neurogenic airway inflammation and mast cell activation, in which weakly acidic reflux is possibly a major factor.
Conclusions : In patients with severe persistent asthma, addition of low‐dose mometasone to SFC50/250 improved spirometric parameters, FENO, and PEF, while an increase in dose from SFC50/250 to SFC50/500 only improved PEF.
Image guided pleural procedures are important in both the diagnosis and management of pleural disease. Pleural aspiration, biopsy and drainage are all proven to be safer and more efficacious using image guidance.
The aim of this article is to review common image guided pleural techniques and the evidence‐base for their application in clinical practice.
Gene expression microarrays are high throughput technologies that can simultaneously measure the expression levels of most known genes in the human genome within a biological sample. The study of gene expression has revealed new understanding into the biological complexities of the cell and can impact the field of medicine by providing new insights into disease. Examining gene expression in samples from patients with pulmonary disease can elucidate molecular mechanisms responsible for disease pathogenesis or uncover novel molecular subtypes within a disease.
Gene expression signatures of disease pathogenesis can further be used to suggest novel therapeutic compounds. Biomarkers can be developed from gene expression data that can aid clinicians in diagnosing disease or can guide ...
Conclusions : Since almost 20% of non‐tuberculosis patients would be erroneously treated for tuberculosis and 25% of patients with tuberculous pleurisy would be missed, pleural fluid IGRAs are not useful for the clinical diagnosis of tuberculous pleurisy.