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Assessing the safety of adding LABAs to inhaled corticosteroids for treating asthma.

Assessing the safety of adding LABAs to inhaled corticosteroids for treating asthma.

N Engl J Med. 2011 Jun 30;364(26):2473-5

Authors: Chowdhury BA, Seymour SM, Levenson MS

PMID: 21714647 [PubMed - indexed for MEDLINE]

New regimens to prevent tuberculosis in adults with HIV infection.

New regimens to prevent tuberculosis in adults with HIV infection.

N Engl J Med. 2011 Jul 7;365(1):11-20

Authors: Martinson NA, Barnes GL, Moulton LH, Msandiwa R, Hausler H, Ram M, McIntyre JA, Gray GE, Chaisson RE

Treatment of latent tuberculosis in patients infected with the human immunodeficiency virus (HIV) is efficacious, but few patients around the world receive such treatment. We evaluated three new regimens for latent tuberculosis that may be more potent and durable than standard isoniazid treatment.

PMID: 21732833 [PubMed - indexed for MEDLINE]

Clinical practice. Glucocorticoid-induced bone disease.

Clinical practice. Glucocorticoid-induced bone disease.

N Engl J Med. 2011 Jul 7;365(1):62-70

Authors: Weinstein RS

PMID: 21732837 [PubMed - indexed for MEDLINE]

Nebulizers in cystic fibrosis: a source of bacterial contamination in cystic fibrosis patients?

CONCLUSIONS: In this sample of patients, despite the inappropriate disinfection techniques, nebulizers were not found to be a source of microbial contamination (Source: Jornal Brasileiro de Pneumologia)

Outpatient treatment of children with severe pneumonia with oral amoxicillin in four countries: the MASS studyTraitement ambulatoire des enfants atteints de pneumonie sévère à l’amoxicilline par voie orale dans 4 pays: L’étude MASS

Conclusions  Clinical treatment failure and adverse event rates among children with severe pneumonia treated at home with oral amoxicillin did not substantially differ across geographic areas. Thus, home‐based therapy of severe pneumonia can be applied to a wide variety of settings.Objectif:  Un récent essai clinique randomisé a démontré que le traitement à domicile de la pneumonie sévère comme définie par l’OMS, avec l’amoxicilline par voie orale était équivalent au traitement en milieu hospitalier et avec des antibiotiques par voie parentérale. Nous avons cherchéà déterminer si ce résultat était généralisable à travers quatre pays.Méthodes:  Etudes d’observation multicentrique au Bangladesh, en Egypte, au Ghana et au Vietnam entre novembre 2005 et mai 20...

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