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Development of Arabic version of Berlin questionnaire to identify obstructive sleep apnea at risk patients

Conclusion: The ABQ is reliable and valid scale in screening patients for the risk of OSA among Arabic-speaking nations, especially in resource-limited settings.

Invasive pneumococcal disease

Introduction Streptococcus pneumoniae, the pneumococcus, is a Gram-positive diplococcus with more than 90 serotypes determined by the polysaccharide composition of its capsule. It is carried asymptomatically in approximately 50% of people.1 It can cause both non-invasive and invasive disease.

Invasive pneumococcal disease (IPD) refers to disease in which the bacterium enters a sterile site such as blood, cerebrospinal fluid (CSF), pleural fluid, joint fluid or pericardial fluid. Non-invasive disease includes otitis media, sinusitis and bronchitis. Among infectious diseases, IPD is a leading cause of morbidity and mortality in children and adults. Vaccination against pneumococcal infection was introduced into the UK routine childhood immunisation programme in 2006 with Prevenar 7 (Pfizer, T...

Evaluation of a transcutaneous carbon dioxide monitor in patients with acute respiratory failure

Conclusions : The accuracy of estimation of the TOSCA transcutaneous electrode (compared with the "gold standard" blood sample gas analysis) was generally good. Moreover, TOSCA presents the advantage of the possibility of continuous non-invasive measurement.

The level of agreement of the two methods of measurement allows us to state that the TOSCA sensor is useful in routine monitoring of adults admitted to an intermediate respiratory unit and undergoing non-invasive ventilation.

New Approach to Treating Asthma in Pregnancy

Researchers in Australia have developed a new treatment plan to reduce asthma flare-ups in pregnancy while minimizing drug exposure to developing fetuses.

This therapy tracks airway inflammation directly by measuring something known as "the fraction of exhaled nitric oxide" -- a marker of inflammation abbreviated as FENO -- in an exhaled breath. By doing so, researchers can identify asthma in pregnant women who have airway inflammation but no symptoms and tailor drug therapy accordingly.

In this study, researchers examined 220 non-smoking women with asthma who were less than 22 weeks pregnant. Half the women were treated based on their clinical symptoms during monthly visits (the control group) and compared to the women in the FENO group, who were tested for airway inflammation. The researchers found the flare-up rate among the women in the FENO group was roughly half that of those in the control group...

Febrile Seizures In Children May Be Triggered By Hyperventilation

New research shows that febrile seizures in children may be linked to respiratory alkalosis, indicated by elevated blood pH and low carbon dioxide levels caused by hyperventilation, and independent of the underlying infection severity.

Febrile seizures were not observed in susceptible children with fevers brought on by gastroenteritis, suggesting that low blood pH levels (acidosis) may have a protective effect. Full findings now appear in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE)...

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