Researchers in Australia have developed a new treatment plan to reduce
asthma flare-ups in
pregnancy while minimizing drug exposure to developing fetuses.
This therapy tracks airway inflammation directly by measuring something known as "the fraction of exhaled nitric oxide" -- a marker of inflammation abbreviated as FENO -- in an exhaled breath. By doing so, researchers can identify asthma in pregnant women who have airway inflammation but no symptoms and tailor drug therapy accordingly.
In this study, researchers examined 220 non-smoking women with asthma who were less than 22 weeks pregnant. Half the women were treated based on their clinical symptoms during monthly visits (the control group) and compared to the women in the FENO group, who were tested for airway inflammation. The researchers found the flare-up rate among the women in the FENO group was roughly half that of those in the control group...